Registry Initiative Across Borders for Atrial Fibrillation in Africa

NCT06674304 | Active Not Recruiting DMC

• 1 other identifier: Mohammed VI UH Tangier
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

Atrial fibrillation is a penalizing disease in several ways: morbidity and mortality, health costs. Several multicenter registries have been published. Until now, no multicenter registry involving several countries has been carried out in Africa. The goal of RIBAT AF Africa is to fill this gap, by recruting patients from twelve african centers. All the centers are a third level Atrial Fibrillation managment facility centers. After recruitment , a complete clinical assessment with analysis of comorbidities will be a priority of this registry to try to understand the epidemiological profile of atrial fibrillation in Africa. Then, we will proceed to the temporal classification of atrial fibrillation according to the 2024 ESC recommendations (type and thromboembolic risk in particular.). After this step, the management will be analyzed with three main axes: management of comorbidities, antithrombotic treatment, rhythm and frequency control. Some therapeutic techniques such as ablation of atrial fibrillation were discussed without much detail because many countries do not yet have access to these expensive techniques. A six-month evaluation is necessary to judge above all the applicability of the measures accessible in all countries and in particular anticoagulant treatment. All these data will be recorded anonymously and electronically. Each country can have access to its own data anytime. The statistical analysis will be carried out by a team within the University Hospital of Tangier , as well as all IT logistics. This team will also organize electronic monitoring and underlying all abnomalities in CRF.

Conditions

Atrial Fibrillation; Atrial Fibrillation (Prevention of Stroke); ATRIAL FIBRILLATION, Syncope

Keywords

Atrial fibrillation; Registry; Africa; Morocco; antithrombotic treatment

Outcome Measures

Primary Outcomes (1)

• Arial fibrillation complications under treatment

  After inclusion, the investigators carry out a six-month follow-up for the patients. During this prospective follow-up period, the primary judgment criterion that must be documented by the investigators is the occurrence of a complication linked to AF or its medical management. The main complications to be looked for are : 1. Death 2. Non fatal stroke or systemic embolic event 3. Non fatal haemorrhagic event 4. Drug side effects

  Six month follow up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

About 3000 patients will be included in the study according to the following criteria: Inclusion criteria * Patients aged ≥ 18 years old * Patients with a documented history of AF for any length of time before enrolment or AF first diagnosed at enrolment visit/hospitalization * Patients previously diagnosed with AF must have at least one documented visit or hospitalization for AF (or AF-related complications) within the last 12 months before enrolment Exclusion criteria * No formal diagnosis of AF in medical records * Only atrial flutter or other atrial tachycardia diagnosed * Participation in a clinical trial (but participation in another registry is allowed)

You may qualify if:

• Patients aged ≥ 18 years old
• Patients with a documented history of AF for any length of time before enrolment or AF first diagnosed at enrolment visit/hospitalization
• Patients previously diagnosed with AF must have at least one documented visit or hospitalization for AF (or AF-related complications) within the last 12 months before enrolment

You may not qualify if:

• No formal diagnosis of AF in medical records
• Only atrial flutter or other atrial tachycardia diagnosed
• Participation in a clinical trial (but participation in another registry is allowed)

Sponsors & Collaborators

• Mohammed VI University Hospital: lead

Study Sites (1)

Mohammed VI University Hospital of Tangier

Tangier, Tangier, 90000, Morocco

Location

MeSH Terms

Conditions

Atrial Fibrillation; Syncope

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Unconsciousness; Consciousness Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of cardiology

Study Record Dates

• First Submitted: November 3, 2024
• First Posted: November 5, 2024
• Study Start: October 22, 2024
• Primary Completion: May 1, 2025
• Study Completion: October 1, 2025
• Last Updated: November 6, 2024

Record last verified: 2024-11

Locations

MO (1)