NCT06671145

Brief Summary

To study new maneuvers to differentiate AVNRT from orthodromic AVRT including VA interval variability at tachycardia induction, SA-VA base and local VA index (difference between local VA interval, measured on the coronary sinus catheter during tachycardia and entrainment, at the site of earliest atrial activity).

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
17mo left

Started Oct 2024

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress53%
Oct 2024Sep 2027

First Submitted

Initial submission to the registry

October 20, 2024

Completed
11 days until next milestone

Study Start

First participant enrolled

October 31, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 4, 2024

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2026

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

September 10, 2027

Last Updated

November 4, 2024

Status Verified

October 1, 2024

Enrollment Period

1.9 years

First QC Date

October 20, 2024

Last Update Submit

October 31, 2024

Conditions

Keywords

AVNRT - orthodromic AVRT

Outcome Measures

Primary Outcomes (1)

  • To differentiate between narrow complex supraventricular tachycardia (AVNRT from orthodromic AVRT during electrothysiological study).

    24 months

Study Arms (2)

group (1)catheter ablation after diagnosis of Atrioventricular Nodal Reentry Tachycardia

ACTIVE COMPARATOR

diagnosis Atrioventricular Nodal Reentry Tachycardia before catheter ablation

Diagnostic Test: catheter ablation

group (2) catheter ablation after diagnosis of orthodromic Atrioventricular Reentry Tachycardia

ACTIVE COMPARATOR

diagnosis of orthodromic Atrioventricular Reentry Tachycardia before catheter ablation

Diagnostic Test: catheter ablation

Interventions

catheter ablationDIAGNOSTIC_TEST

Catheter ablation after differentiating Atrioventricular Nodal Reentry Tachycardia from Orthodromic Atrioventricular Reentry Tachycardia during electrophysiological study.

group (1)catheter ablation after diagnosis of Atrioventricular Nodal Reentry Tachycardiagroup (2) catheter ablation after diagnosis of orthodromic Atrioventricular Reentry Tachycardia

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All patients with documented narrow complex supraventricular tachycardia presented to electrophysiology lab including all age and sex patients (in Assiut university cath. lab) and proved to be AVNRT or orthodromic AVRT.

You may not qualify if:

  • Atrial tachycardia
  • Atrial flutter.
  • Atrial fibrillation.
  • Manifest preexcitation on surface ECG -

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Doaa Ahmed Fouad, pro

    Assiut University

    PRINCIPAL INVESTIGATOR
  • Heba Mahmoud Abdel Mohsen El- naggar, Ass. pro

    Assiut University

    PRINCIPAL INVESTIGATOR
  • marwan sayed mahmoud, doctor

    Assiut University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hossam EL Din mohamed, Resident

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
doctor

Study Record Dates

First Submitted

October 20, 2024

First Posted

November 4, 2024

Study Start

October 31, 2024

Primary Completion (Estimated)

September 10, 2026

Study Completion (Estimated)

September 10, 2027

Last Updated

November 4, 2024

Record last verified: 2024-10