NCT06670677

Brief Summary

Because Aktiia S.A. has been the first-ever company to put in the market an Optical Blood Pressure Monitoring device, there is a need for Aktiia S.A. to correlate for the first time continual Blood Pressure monitoring and the evolution of environmental and health factors to improve hypertension management.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15,000

participants targeted

Target at P75+ for all trials

Timeline
110mo left

Started May 2025

Longer than P75 for all trials

Geographic Reach
2 countries

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress10%
May 2025May 2035

First Submitted

Initial submission to the registry

October 23, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 1, 2024

Completed
6 months until next milestone

Study Start

First participant enrolled

May 12, 2025

Completed
10.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2035

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2035

Last Updated

May 14, 2025

Status Verified

May 1, 2025

Enrollment Period

10.1 years

First QC Date

October 23, 2024

Last Update Submit

May 12, 2025

Conditions

Keywords

hypertensionblood pressureHypertensivecardiovascular diseasescardiovascular riskprediction

Outcome Measures

Primary Outcomes (1)

  • Multivariate models relating data from 24/7 Aktiia the G1 device continual BP monitoring with sociodemographic - lifestyle - and health factors

    Strength and direction of the correlation coefficient between continuous blood pressure readings and various survey-derived factors such as sociodemographic variables, lifestyle habits, and health metrics.

    10 years

Secondary Outcomes (1)

  • Global scale projections of the benefit of the early awareness of hypertension with the spot-check Aktiia G2C device at the fingertip

    10 years

Study Arms (3)

ARM 1 G1 Aktiia users Android

Research participants are Aktiia G1 users with Android operating system, i.e. individuals who already purchased the Aktiia G1 device out of the context of the study, located in Switzerland, Germany or UK, and owning a smartphone with Android operating system.

Other: Lifestyle survey completionOther: Unlimited on-demand blood pressure measurements with G2COther: Continual blood pressure measurements with G1

ARM 2 G1 AKTIIA users iOS

Research participants are Aktiia G1 users with iOS operating system, i.e. individuals who already purchased the Aktiia G1 device out of the context of the study, located in Switzerland, Germany or UK, and owning a smartphone with iOS operating system.

Other: Lifestyle survey completionOther: Unlimited on-demand blood pressure measurements with G2COther: Continual blood pressure measurements with G1

ARM 3 non-Aktiia-G1-users Android & iOS

Research participants are non-Aktiia-G1 users (they do not own an Aktiia G1 device at their inclusion in the study), located in Switzerland, Germany or UK, and owning a smartphone with either iOS or Android operating system.

Other: Lifestyle survey completionOther: Unlimited on-demand blood pressure measurements with G2C

Interventions

For the next 10 years, starting at their inclusion in the research project and every 6 months thereafter: fill in an online survey on their lifestyle- health- socioeconomic environment. The completion of a survey lasts 5min maximum.

ARM 1 G1 Aktiia users AndroidARM 2 G1 AKTIIA users iOSARM 3 non-Aktiia-G1-users Android & iOS

For the next 10 years: take unlimited on-demand measurements with the Aktiia G2C feature (finger measurement) while seated

ARM 1 G1 Aktiia users AndroidARM 2 G1 AKTIIA users iOSARM 3 non-Aktiia-G1-users Android & iOS

For the next 10 years: wear their 24/7 Aktiia G1 device continuously as they would outside the context of the research project.

ARM 1 G1 Aktiia users AndroidARM 2 G1 AKTIIA users iOS

Eligibility Criteria

Age21 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any subjects that respect the study inclusion criteria.

You may qualify if:

  • Adult subjects aged 21 to 85 years old
  • Subjects living in Switzerland, Germany or in the UK
  • Subjects that are:
  • Aktiia users owning a smartphone with either iOS or Android operating system (ARMs 1 and 2); or Aktiia non-users owning a smartphone with iOS or Android operating system (ARM 3)
  • Subjects agreeing to follow the study procedures.

You may not qualify if:

  • Subjects suffering from sustained cardiac arrhythmias that can lead to weak or unstable pressure pulses including resting tachycardia (heart rate at rest \> 120bpm) and atrial fibrillation;
  • Subjects suffering from pathologies that systematically reduce peripheral perfusion including Raynaud's disease, diabetes, renal dysfunctions (eGFR \< 30mL / min / 1.73 m2), untreated hyper-/ hypothyroidism, pheochromocytoma, or arteriovenous fistula;
  • Subjects suffering from polyneuropathy;
  • on pregnant women;
  • Subjects with damaged / injured skin at the wrists (for bracelet measurements) or at index fingers (for camera measurements)
  • Subjects with amputated index fingers (for camera measurements) or amputated upper limb;
  • Subjects below 21 years old and above 85 years old.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Fully remote study- no physical investigational site

Lausanne, Switzerland

RECRUITING

Fully remote study- no physical investigational site

London, United Kingdom

RECRUITING

MeSH Terms

Conditions

HypertensionCardiovascular Diseases

Condition Hierarchy (Ancestors)

Vascular Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 23, 2024

First Posted

November 1, 2024

Study Start

May 12, 2025

Primary Completion (Estimated)

May 31, 2035

Study Completion (Estimated)

May 31, 2035

Last Updated

May 14, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations