NCT06667440

Brief Summary

The aim of this randomized controlled trial is to observe the effectiveness of cryotherapy application in nulliparous women with primary dysmenorrhea regarding pain intensity, sleep quality and quality of life. It is also intended to analyse whether the levels of physical activity and the socioeconomic status of the participants are determining factors.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
180

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2024

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 10, 2024

Completed
2 months until next milestone

First Posted

Study publicly available on registry

October 31, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

November 4, 2024

Status Verified

September 1, 2024

Enrollment Period

6 months

First QC Date

September 10, 2024

Last Update Submit

October 30, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • NUMERICAL RATING SCALE (NRS)

    Subjective measure used to assess the intensity of pain or other symptoms on a scale from 0 to 10, where 0 indicates no pain or symptom and 10 represents the worst possible experience. Interpretation: Higher scores indicate greater severity, allowing clinicians to evaluate changes in symptoms over time or the effectiveness of interventions.

    From enrollment to the end of the treatment at 6 months

Secondary Outcomes (2)

  • Pittsburgh Quality Sleep Index (PQSI)

    From enrollment to the end of the treatment at 6 months

  • World Health Organization Quality of Life Brief Version (WHOQOL-BREF)

    From enrollment to the end of the treatment at 6 months

Other Outcomes (2)

  • International Physical Activity Questionnaire-Short Form (IPAQ-SF)

    Prior to initiation of treatment

  • Kuppuswamy Socioeconomic Status Scale

    Prior to initiation of treatment

Study Arms (2)

CRIOTHERAPY

EXPERIMENTAL

Women in the intervention group will apply cryotherapy on their hypogastrium with a coldpack

Other: Cryotherapy

CONTROL

NO INTERVENTION

Interventions

Women in the intervention group will apply cryotherapy on their hypogastrium with a coldpack

CRIOTHERAPY

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Menstrually active women
  • Menstrual cycles that vary between 24 and 38 days according to the OASH
  • menstrual periods between 3 and 7 days, and
  • Pain lasting from 1 to 3 days

You may not qualify if:

  • Patients suffering diseases that generate secondary dysmenorrhea, with systemic or psychiatric diseases, and patients with a history of use of hormonal medication, birth control pill, or intrauterine devices

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Malaga

Málaga, MALAGA, 29076, Spain

Location

MeSH Terms

Conditions

Dysmenorrhea

Interventions

Cryotherapy

Condition Hierarchy (Ancestors)

Menstruation DisturbancesPathologic ProcessesPathological Conditions, Signs and SymptomsPelvic PainPainNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Profesor Titular

Study Record Dates

First Submitted

September 10, 2024

First Posted

October 31, 2024

Study Start

June 1, 2024

Primary Completion

December 1, 2024

Study Completion

December 1, 2024

Last Updated

November 4, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Locations