NCT06663085

Brief Summary

To evaluate the differences splanchnic oxygen saturation in preterm infants receiving red blood cell transfusion with and without enteral feeding, and their outcomes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 24, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 29, 2024

Completed
1 day until next milestone

Study Start

First participant enrolled

October 30, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2024

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2025

Completed
Last Updated

October 29, 2024

Status Verified

October 1, 2024

Enrollment Period

2 months

First QC Date

October 24, 2024

Last Update Submit

October 28, 2024

Conditions

Keywords

transfusionnirssplanchnic oxygenationpreterm neonateenteral feeds

Outcome Measures

Primary Outcomes (1)

  • cerebral splanchnic oxygenation ratio using nirs

    percentage of splanchnic oxygenaation divided with cerebral oxygenation

    from enrollment to 48 hours after transfusion

Study Arms (2)

control group not received enteral feeding

NO INTERVENTION

control group not received enteral feeding during blood transfusion

intervention group received enteral feeding

ACTIVE COMPARATOR

intervention group still received enteral feeding during blood transfusion

Dietary Supplement: Enteral feeding

Interventions

Enteral feedingDIETARY_SUPPLEMENT

intervention group received enteral feeding breastmilk during transfusion

Also known as: breastmilk
intervention group received enteral feeding

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Infant with gestational age \< 37 weeks
  • Planned to receive blood transfusion
  • Had received minimum 25 ml/kg/day enteral feeding
  • in stable condition

You may not qualify if:

  • Infant with multiple congenital anomalies
  • Infant with suspected/confirmed genetic anomalies
  • Parents or family did not sign the informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr Sardjito General Hospital

Yogyakarta, Special Region of Yogyakarta, 62, Indonesia

Location

MeSH Terms

Interventions

Enteral Nutrition

Intervention Hierarchy (Ancestors)

Feeding MethodsTherapeuticsNutritional SupportNutrition Therapy

Central Study Contacts

leksmana hidayatullah, medical doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Model Details: control group: not received enteral feeding during transfusion intervention group: received enteral feeding
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

October 24, 2024

First Posted

October 29, 2024

Study Start

October 30, 2024

Primary Completion

December 30, 2024

Study Completion

January 15, 2025

Last Updated

October 29, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

the data will not be planned to share until publication, if any person want to see the data can contact the investigator by email

Locations