Effect of Practicing Yoga and Meditation on Cortisol Hormone, Immunoglobulin a and Metabolic Parameter Among Medical Students

NCT06661603 | Recruiting DMC

• 1 other identifier: GSY (Goodbye Stress with Yoga)
• Study Type: interventional
• Target: 280
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial aims to develop and test a yoga intervention to improve cortisol hormone rhythm, immunoglobulin A, and metabolic markers among medical students. The development of the yoga protocol, "GSY Goodbye Stress with Yoga Proto-col," was a collaborative effort involving a certified yoga trainer, medical researcher, and experienced yogis from India. GSY yoga intervention, which includes yoga asanas poses, breathing techniques, and guided meditation, may reduce stress levels, improve immunity, and enhance other metabolic parameters in medical students.

Conditions

Healthy; Adult Children

Keywords

Medical students; Yoga; Cortisol Hormone; Immunoglobulin; mental health

Outcome Measures

Primary Outcomes (4)

• Effect of GSY Yoga Intervention in the Improvement of Immunoglobulin A among Medical Students

  Samples of saliva cortisol will be collected to analyse diurnal cortisol rhythm , at the beginning and the end of the first and the last yoga class to determine immediate and longitudinal effects and to measure the diurnal rhythms of immunoglobulin.

  upto 10 weeks

• Efficacy of GSY yoga intervention in the reduction of cortisol hormone rhythm

  Samples of saliva cortisol will be collected, at the beginning and the end of the first and the last yoga class to determine immediate and longitudinal effects and to measure the diurnal rhythms of cortisol.

  upto 10 weeks

• Efficacy of GSY yoga intervention in the cortisol hormone by using hair cortisol concentration

  Samples of hair cortisol will be collected to measure hair cortisol concentration for analyzing the long-term cortisol level in individuals, at the beginning and the end of the first and the last yoga class

  10 weeks

• Effect of 10 weeks yoga intervention on immune and metabolic parameter among medical students

  Blood sample will be collected to analyse Immune parameter, including Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, and Metabolic parameter including, Fasting Blood Glucose FBG, HBA1C, LDL,HDL,total cholesterol, triglycerides, and non-HDL at the beginning and the end of the first and the last yoga class to determine immediate and longitudinal effects. .

  Upto 10 weeks

Secondary Outcomes (6)

• Changes in Quality of life

  upto 10 weeks

• Changes in sleep quality

  upto 10 weeks

• Changes in physical activity

  upto 10 weeks

• Changes in stress reduction

  upto 10 weeks

• Changes in emotional regulation

  upto 10 weeks

Study Arms (2)

GSY Yoga Intervention

EXPERIMENTAL

GSY Goodbye Stress with Yoga Protocol Full body warm-up and light stretching exercise 15 min Performing various yoga postures - including standing, sitting, prone, and supine yoga postures (Asanas) 50 min Breathing exercises = (Pranayama)10 min and Meditation15 min \*The development of the yoga protocol, named "GSY Goodbye Stress with Yoga Protocol," was a collaborative effort involving a certified yoga trainer, a medical researcher, and experienced yogis from India.

Behavioral: GSY Yoga Intervention

Control Group

NO INTERVENTION

The participants who don't receive any kind of therapy, which means the control group with standard care and without any treatment or intervention.

Interventions

GSY Yoga Intervention BEHAVIORAL

In the GSY yoga intervention, where participants received 90 minutes/week yoga intervention for duration of 10 weeks.

GSY Yoga Intervention

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• Students with illnesses (such as recent injuries, chronic pain, or significant arthritis) that would make it unsafe for them to take part in a yoga intervention will be excluded from the study.

Sponsors & Collaborators

• University of Pecs: lead

Study Sites (1)

University of Pécs

Pécs, Pécs, 7621, Hungary

RECRUITING

Related Publications (3)

• Chauhan S, Babu AM, Galgalo DA, Melczer C, Premusz V, Karsai I. Effect of yoga in medical students to reduce the level of depression, anxiety, and stress: pilot study (Goodbye Stress with Yoga GSY). BMC Complement Med Ther. 2024 May 24;24(1):203. doi: 10.1186/s12906-024-04496-0.

  PMID: 38790041 BACKGROUND

• Chauhan S, Najaf SS, Nagy Z, Al-Jawarneh M, Nagy T, Miseta A, Premusz V, Karsai I. An exploratory study on the changes in immune and metabolic parameters by 10 weeks of yoga intervention among medical students. Sci Rep. 2025 Nov 5;15(1):38730. doi: 10.1038/s41598-025-22421-4.

  PMID: 41193511 DERIVED

• Chauhan S, Najaf SS, Gergely L, Kinga KA, Karsai I, Premusz V. Impact of 10 Weeks of Yoga Intervention on Mental Health and Overall Well-Being Among Medical Students: GSY Study. Sports (Basel). 2025 Apr 10;13(4):114. doi: 10.3390/sports13040114.

  PMID: 40278740 DERIVED

Related Links

• Pilot Study Results

MeSH Terms

Conditions

Psychological Well-Being

Condition Hierarchy (Ancestors)

Personal Satisfaction; Behavior

Study Officials

• Shalini Chauhan

  Assistant Professor, PhD student University of Pécs

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Shalini Chauhan

CONTACT

+36-72/501-500/61682; doktoriiskola@etk.pte.hu

Shalini Chauhan

CONTACT

+36 (72) 513-678; doktoriiskola@etk.pte.hu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 23, 2024
• First Posted: October 28, 2024
• Study Start: February 7, 2022
• Primary Completion: June 1, 2025
• Study Completion: July 1, 2025
• Last Updated: December 9, 2024

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

HU (1)