Is Harvesting the Peroneus Brevis an Alternative in Anatomic Ankle Ligament Reconstruction

NCT06655350 | Completed

• 1 other identifier: IRBN752024/CHUSTE
• Study Type: observational
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

Severe ankle sprains are the most frequent reason for emergency trauma consultations. Between 30% and 80% of sprains result in sequelae such as pain, joint derangement or instability. Ankle instability can itself lead to osteoarthritis if left untreated (1st cause of post-traumatic ankle osteoarthritis). To treat instability, ligament reconstruction is performed by harvesting the tendon of the gracilis muscle (inserted at knee level) to replace the damaged ankle ligaments. This tendon is also used for other ligament reconstructions (anterior cruciate ligament), so is not always harvested. Moreover, it represents an invasive procedure at a distance from the site of interest (the ankle), and can cause sensory nerve damage (20-60% of cases). For a long time, half of the peroneus brevis tendon was harvested as part of a now-defunct ankle stabilization technique (Hemi-Castaing). This tendon does, however, play a role in stabilizing the ankle.

Conditions

Ankle Disease; Ankle (Ligaments); Instability (Old Injury)

Keywords

Ankle instability; Graft; Peroneus brevis; Ankle ligament reconstruction

Outcome Measures

Primary Outcomes (1)

• Peroneus brevis diameter of a native ankle and at one-year postoperative harvested ankle.

  Cross section area (mm²) at 40, 30, 20mm above the tip of the fibula, and 20mm from 5th metatarsal basis.

  Year : 1

Secondary Outcomes (1)

• Peroneus brevis MRI aspect of a native ankle and at one-year postoperative harvested ankle.

  Year : 1

Study Arms (2)

Harvested ankle

Other: MRI; Other: Measure

Native ankle

Other: MRI; Other: Measure

Interventions

MRI OTHER

Morphological data on the tendon (appearance) will be collected on the harvested side and on the healthy side from an MRI analysis carried out systematically after Haemi-Castaing-type surgery.

Harvested ankle; Native ankle

Measure OTHER

Morphological data on the tendon (diameter) will be collected on the harvested side and on the healthy side from an MRI analysis carried out systematically after Haemi-Castaing-type surgery.

Harvested ankle; Native ankle

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients at Saint-Etienne University Hospital who underwent Haemi-Castaing-type ankle stabilisation surgery.

You may qualify if:

• Adult one year after peroneus brevis harvesting (Hemi-Castaing)

You may not qualify if:

• No.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Saint Etienne: lead

Study Sites (1)

CHU de Saint-Etienne

Saint-Priest-en-Jarez, 42270, France

Location

MeSH Terms

Interventions

Weights and Measures

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

• Pierre-Henri Vermorel, MD

  CHU de Saint-Etienne

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 22, 2024
• First Posted: October 23, 2024
• Study Start: September 6, 2024
• Primary Completion: October 11, 2024
• Study Completion: October 11, 2024
• Last Updated: October 23, 2024

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)