Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts: Randomized Controlled Clinical Trial

NCT06653868 | Recruiting DMC

• 1 other identifier: per631
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 2

Brief Summary

In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?

Conditions

Bone Loss, Alveolar

Outcome Measures

Primary Outcomes (1)

• bone changes

  superimposition

  6 months

Secondary Outcomes (1)

• pink esthetic score

  6 months

Study Arms (2)

immediate implant placement surgery with filling the gap distance with alloplastic sticky graft

EXPERIMENTAL

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with alloplast.

Procedure: dental implant with bone augmentation

immediate implant placement surgery with filling the gap distance with xenogenic sticky bone

EXPERIMENTAL

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with xenograft.

Procedure: dental implant with bone augmentation

Interventions

dental implant with bone augmentation PROCEDURE

gap distance augmentation with bone graft

Also known as: gap distance augmentation

immediate implant placement surgery with filling the gap distance with alloplastic sticky graft; immediate implant placement surgery with filling the gap distance with xenogenic sticky bone

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with healthy systemic condition (Mazzotti et al., 2023).
• Age from 20-50 years old
• Patients must be free of any systemic disease which could influence the surgical procedure.
• Tooth involved in the esthetic zone.
• Sufficient hard and soft tissue volume in vertical and buccolingual direction
• Natural teeth adjacent to the involved tooth will be required to be free from infection.
• Controlled oral hygiene.
• Indication for tooth extraction included (Degidi et al., 2012);
• Endodontic failures
• Untreatable caries
• Non- restorable teeth
• Vertical root fracture
• Remaining roots

You may not qualify if:

• \- 1.Pregnant females 2.Smokers (Khuller, 2009) 3.Unmotivated and uncooperative patients with poor oral hygiene 4.Patients with habits that may compromise the longevity and affect the result of the study as alcoholism or parafunctional habits.
• Presence of acute dento-alveolar infection.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (2)

Cairo University

Cairo, Egypt

RECRUITING

Cairo University

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Alveolar Bone Loss

Interventions

Dental Implants

Condition Hierarchy (Ancestors)

Bone Resorption; Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Dental Materials; Biomedical and Dental Materials; Dental Prosthesis; Prosthodontics; Dentistry; Prostheses and Implants; Equipment and Supplies; Manufactured Materials; Technology, Industry, and Agriculture

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: bassant mohye

Study Record Dates

• First Submitted: October 21, 2024
• First Posted: October 22, 2024
• Study Start: October 20, 2024
• Primary Completion: March 20, 2026
• Study Completion: March 20, 2026
• Last Updated: October 22, 2024

Record last verified: 2024-10

Locations

EG (2)