NCT06643507

Brief Summary

treatment of miller class III RT2 gingival recession using modified vista technique using connective tissue graft vs albumin PRF

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for phase_2

Timeline
9mo left

Started Apr 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress59%
Apr 2025Jan 2027

First Submitted

Initial submission to the registry

October 10, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 16, 2024

Completed
6 months until next milestone

Study Start

First participant enrolled

April 20, 2025

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 20, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2027

Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

1.7 years

First QC Date

October 10, 2024

Last Update Submit

March 19, 2026

Conditions

Keywords

gingival recession, plastic surgery, soft tissue management

Outcome Measures

Primary Outcomes (1)

  • mean root coverage

    primary outcome measures of mean root coverage in millimeters by UNC15 periodontal probe

    6 months

Secondary Outcomes (6)

  • the percentage of mean root coverage

    6 months

  • the percentage of complete root coverage

    6 months

  • recession depth

    6 months

  • recession width

    6 months

  • keratinized tissue width

    6 months

  • +1 more secondary outcomes

Study Arms (2)

patients with gingival recession control group

ACTIVE COMPARATOR

patients with gingival recessions of miller class III /RT2 the control group will be treated with modified vista technique using connective tissue graft

Other: Connective tissue graft

patients with gingival recession interventional group

EXPERIMENTAL

patients with gingival recessions of miller class III /RT2 the interventional group will be treated with modified vista technique using albumin PRF

Biological: ALB-PRF

Interventions

regenerative properties

patients with gingival recession control group
ALB-PRFBIOLOGICAL

regenerative properties

patients with gingival recession interventional group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years old good oral hygiene

You may not qualify if:

  • smokers patients with poor oral hygiene

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry Cairo University

Cairo, 4240101, Egypt

RECRUITING

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesPeriodontal Atrophy

Study Officials

  • Enji EA Ahmed, BDS.MDS.PHD

    Cairo University

    STUDY DIRECTOR
  • Sarah SE Elbanna, BDS.MDS.PHD

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
clinical evaluation of the modified VISTA technique (M-VISTA)using Albumin -platelet rich fibrin (Alb-PRF)versus connective tissue graft (CTG)in the treatment of multiple miller class III/RT2recessions : a randomized clinical trial

Study Record Dates

First Submitted

October 10, 2024

First Posted

October 16, 2024

Study Start

April 20, 2025

Primary Completion (Estimated)

December 20, 2026

Study Completion (Estimated)

January 30, 2027

Last Updated

March 20, 2026

Record last verified: 2026-03

Locations