NCT06639893

Brief Summary

The objective of this clinical trial is to evaluate crestal bone loss every three months at time of overdenture insertion, 3, 6, 9, 12 months from overdenture use. Also, to evaluate prosthesis satisfaction. All participants will receive conventional complete dentures, followed by two intraforaminal implants. After healing time, fabrication of secondary copings in all cases according to randomized groups for final overdenture insertion.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at P50-P75 for early_phase_1

Timeline
Completed

Started Aug 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2024

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

October 9, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 15, 2024

Completed
Last Updated

October 15, 2024

Status Verified

October 1, 2024

Enrollment Period

1 year

First QC Date

October 9, 2024

Last Update Submit

October 10, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Crestal bone loss.

    The aim of this study was to evaluate crestal peri implant bone loss in mandibular telescopic implant retained overdenture with milled titanium, milled poly-ether ketone ketones and 3D printed chrome cobalt secondary copings. Crestal bone loss evaluated every three months using standardized digital periapical radiograph at time of overdenture insertion, 3, 6, 9, and after 12 months from overdenture use.

    one year

Study Arms (3)

Milled Titanium secondary copings

ACTIVE COMPARATOR
Procedure: Telescopic overdenture

3D printed chrom cobalt copings.

EXPERIMENTAL
Procedure: Telescopic overdenture

Milled Poly-ether Ketone Ketones copings.

EXPERIMENTAL
Procedure: Telescopic overdenture

Interventions

Telescopic overdenture with two dental implants in intraforaminal area for mandible.

3D printed chrom cobalt copings.Milled Poly-ether Ketone Ketones copings.Milled Titanium secondary copings

Eligibility Criteria

Age55 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Sufficient remaining bone in height, width and thickness in the interforaminal area to allow installation of at least 3.3 mm diameter and 8 mm length implants.
  • Adequate amount of interarch space of at least 12mm.
  • Age range from 55 to 75 years old age.

You may not qualify if:

  • Systemic and metabolic diseases that may affect osseointegration.
  • Patients receiving bisphosphonates therapy.
  • Patients under radiotherapy or chemotherapy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

EL Minia University

Minya, Egypt

Location

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecturer of prosthodontics

Study Record Dates

First Submitted

October 9, 2024

First Posted

October 15, 2024

Study Start

August 1, 2023

Primary Completion

August 1, 2024

Study Completion

October 1, 2024

Last Updated

October 15, 2024

Record last verified: 2024-10

Locations