Comparison of Device Based Inspiratory Muscle Training and Thera-band Resistive Training in Healthy Adults

NCT06632847 | Completed DMC

• 1 other identifier: Umaila Rafique
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the impact of inspiratory muscle training and Thera-band resistive training on pulmonary function and diaphragmatic strength of healthy adults. This trail investigate whether IMT can improve pulmonary function and diaphragmatic strength of healthy adults as well as overall respiratory health.

Conditions

Healthy Young Adults

Keywords

Inspiratory muscle training; Thera-band resistive training; Healthy young adults

Outcome Measures

Primary Outcomes (3)

• Peak Expiratory Flow Rate (PEFR)

  peak expiratory flow rates measured through digital spirometer.3 zones of measurements are commonly used to interpret peak flow rates. Normal value of PEFR is 80 to 100%.Green zone indicates 80 to 100% normal peak flow reading, yellow zone indicates 50 to 79 %of normal peak flow readings, and red zone indicates less than 50% of normal peak flow reading.

  6 weeks

• Forced Vital Capacity (FVC)

  Forced Vital Capacity (FVC) Forced vital capacity (FVC) measured through digital spirometer. If the value of FVC is within 80% of the reference value, the results are considered normal. Changes in FVC from baseline to 3rd week and after 6 weeks day of intervention will be assessed.

  6 week

• Forced Expiratory volume in 1sec (FEV1)

  Forced expiratory volume in 1sec (FEV1) measured through digital spirometer. If the value of FEV1 is within 80% of the reference value, the results are considered normal.

  6 week

Study Arms (2)

IMT with device

EXPERIMENTAL

IMT is a therapeutic approach designed to improve respiratory muscle strength and endurance. In this trail, participants will engage in a structured regimen of inspiratory exercises with high resistance. participants will perform inspiratory muscle exercises using the power-breathe device that provide intermediate to high resistance, with focus on both intensity and volume. The protocol involves 4 to 5 session per week.

Other: IMT based Resistance training

Thera-band resistive training

ACTIVE COMPARATOR

Participant will engage in a structured training that involving Thera-band resistance training. Participants use different color of thera-band that provides different resistance. The regimen includes 3 session per week using different colors of band.

Other: Theraband Resistive training

Interventions

IMT based Resistance training OTHER

IMT with device group is trained twice daily, with the morning session and afternoon session. The intensity will increase progressively in this group, starting at 60% Maximal Inspiratory Pressure (MIP) and reaching 75% by the end of study. POSITION: Patient will be in sitting position. FREQUENCY: 4 TO 5 times per week. INTENSITY: 60 to 75% of MIP (gradually increment the load by 10%every 2 weeks to reach 75 to 80 %MIP). Time: 15 to 20 minutes.

IMT with device

Theraband Resistive training OTHER

IMT training is form of exercise designed to strengthen the muscle that are involve in inhalation, primarily the diaphragm and intercostal muscles. Thera-band resistive training perform twice daily, with morning and afternoon session. Training will be perform 3 times per week. POSITION: patient will be in standing position. INTENSITY: moderate intensity (black and green thera-band used to provide medium resistance). Time: 15 to 20 minutes

Thera-band resistive training

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Both male and female participants.
• to 35 years
• FEV1/FVC ratio above 60%
• Non-smokers

You may not qualify if:

• Acute illness within last 2 weeks
• Obese patients whose BMI greater than 30kg
• Patient with history of chronic airflow limitation or any diagnosed disease.
• Patient with acute infection.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Railway General Hospital

Rawalpindi, Punjab Province, 46300, Pakistan

Location

Related Publications (3)

• Fernandez-Lazaro D, Corchete LA, Garcia JF, Jerves Donoso D, Lantaron-Caeiro E, Cobreros Mielgo R, Mielgo-Ayuso J, Gallego-Gallego D, Seco-Calvo J. Effects on Respiratory Pressures, Spirometry Biomarkers, and Sports Performance after Inspiratory Muscle Training in a Physically Active Population by Powerbreath(R): A Systematic Review and Meta-Analysis. Biology (Basel). 2022 Dec 29;12(1):56. doi: 10.3390/biology12010056.

  PMID: 36671748 BACKGROUND

• Qin L, Liu S, Hu S, Feng L, Wang H, Gong X, Xuan W, Lu T. The Effect of Inspiratory Muscle Training on Health-Related Fitness in College Students. Int J Environ Res Public Health. 2024 Aug 17;21(8):1088. doi: 10.3390/ijerph21081088.

  PMID: 39200697 BACKGROUND

• Van Hollebeke M, Gosselink R, Langer D. Training Specificity of Inspiratory Muscle Training Methods: A Randomized Trial. Front Physiol. 2020 Dec 3;11:576595. doi: 10.3389/fphys.2020.576595. eCollection 2020.

  PMID: 33343384 BACKGROUND

Study Officials

• Suman Sheraz, Phd

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 8, 2024
• First Posted: October 9, 2024
• Study Start: April 1, 2025
• Primary Completion: June 30, 2025
• Study Completion: July 15, 2025
• Last Updated: August 19, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)