NCT06629935

Brief Summary

The aim of this study is to investigate the effect of different instrument modifications on the customized osteotomy of the lateral nasal wall in Le Fort I surgery, focusing on the level of lateral nasal wall fractures and the separation pattern of the pterygomaxillary junction. The primary hypothesis is blade osteotome is useful and facilitate the fracture line in ideal level both for lateral nasal wall and the pterygomaxillary junction.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
46

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 12, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 12, 2024

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

October 4, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 8, 2024

Completed
Last Updated

October 8, 2024

Status Verified

October 1, 2024

Enrollment Period

3 months

First QC Date

October 4, 2024

Last Update Submit

October 4, 2024

Conditions

Keywords

orthognthic surgeryle fort Ilateral nasal wallpterygomaxillary junction

Outcome Measures

Primary Outcomes (1)

  • lateral nasal wall fracture type

    Class 1: Fracture at the osteotomy line Class 2: Fracture 2-4 mm above the osteotomy line Class 3: Fracture more than 4 mm above the osteotomy line

    6 months

Secondary Outcomes (1)

  • pterygomaxillary junction fracture type

    6 months

Study Arms (2)

Nievert osteotomy group

EXPERIMENTAL

lateral nasal wall osteotomy has been performed with single guided Nievert osteotome.

Procedure: orthognathic surgery

Blade osteotomy group

ACTIVE COMPARATOR

lateral nasal wall osteotomy has been performed with blade osteotome.

Procedure: orthognathic surgery

Interventions

Le Fort I surgery

Blade osteotomy groupNievert osteotomy group

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients requiring Le Fort I or bimaxillary surgery
  • Patients who have not previously undergone Le Fort I or bimaxillary surgery (revision)
  • Patients without cleft lip or palate
  • Patients with no history of midface fractures or craniofacial trauma

You may not qualify if:

  • Patients with cleft lip and/or palate requiring orthognathic surgery
  • Patients with a history of trauma needing orthognathic surgery for malocclusion correction
  • Patients who have previously undergone orthognathic surgery and require revision surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bezmialem Vakıf Universty

Istanbul, Fatih, 34093, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hemorrhage

Interventions

Orthognathic Surgery

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Surgery, OralDentistry

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2024

First Posted

October 8, 2024

Study Start

May 1, 2024

Primary Completion

August 12, 2024

Study Completion

August 12, 2024

Last Updated

October 8, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will not share

Locations