NCT06629285

Brief Summary

A randomized controlled trial study conducted by comparing the VAS score, swelling condition, knee ROM and patient's satisfactory score between applying ice pack cold therapy and applying continuous compressive cryotherapy in a postoperative three-day period of anterior cruciate ligament reconstruction surgery patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Jun 2023

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2023

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2024

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 3, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 8, 2024

Completed
Last Updated

October 8, 2024

Status Verified

June 1, 2023

Enrollment Period

1.1 years

First QC Date

October 3, 2024

Last Update Submit

October 3, 2024

Conditions

Outcome Measures

Primary Outcomes (3)

  • Visual Analog Scale

    Compare postoperative Pain score

    3 days postoperative

  • Knee effusion

    Compare knee swelling rate

    3 days postoperative

  • Knee range of motion

    Range of motion in knee postoperatively

    3 days postoperative

Study Arms (2)

Conventional ice treatment

ACTIVE COMPARATOR
Procedure: Conventional ice treatment

Continuous compression cryotherapy

EXPERIMENTAL
Procedure: Continuous compression cryotherapy

Interventions

Using continuous compression cryotherapy around knee after anterior cruciate ligament reconstruction for 3 postoperative days

Continuous compression cryotherapy

Using icepack around knee after anterior cruciate ligament reconstruction for 3 postoperative days

Conventional ice treatment

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Having anterior cruciate ligament reconstruction
  • Agree to be enrolled in study

You may not qualify if:

  • Complex knee injury
  • Raynard's disease
  • Sensitive to low temperature
  • Do not want to use cryotherapy
  • Have vascular disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Medical Center, Ho Chi Minh city

Ho Chi Minh City, Ho Chi Minh, 700000, Vietnam

Location

Related Publications (1)

  • Tran LTK, Nguyen QTK, Hoang HQ, Nguyen B, Pham VQ. Enhancing patient outcomes after anterior cruciate ligament reconstruction with continuous cryotherapy: A Nursing-Focused Randomized Control Trial. Int J Orthop Trauma Nurs. 2025 Aug;58:101206. doi: 10.1016/j.ijotn.2025.101206. Epub 2025 Jun 11.

MeSH Terms

Conditions

Pain, PostoperativeAnterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsKnee InjuriesLeg InjuriesWounds and Injuries

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2024

First Posted

October 8, 2024

Study Start

June 1, 2023

Primary Completion

July 1, 2024

Study Completion

July 1, 2024

Last Updated

October 8, 2024

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will share

Locations