NCT06625138

Brief Summary

This study will involve the recruitment of adult patients with hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band. Our goal will be to measure the performance of latex bands vs non-latex bands.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
164

participants targeted

Target at P75+ for not_applicable

Timeline
4mo left

Started Aug 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress81%
Aug 2024Oct 2026

Study Start

First participant enrolled

August 30, 2024

Completed
12 days until next milestone

First Submitted

Initial submission to the registry

September 11, 2024

Completed
22 days until next milestone

First Posted

Study publicly available on registry

October 3, 2024

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Expected
Last Updated

October 28, 2024

Status Verified

October 1, 2024

Enrollment Period

1.1 years

First QC Date

September 11, 2024

Last Update Submit

October 24, 2024

Conditions

Keywords

hemorrhoidbanding

Outcome Measures

Primary Outcomes (1)

  • Hemorrhoid Band Efficacy

    hemorrhoidal bleeding and prolapse symptoms following ligation.

    2-4 months

Secondary Outcomes (1)

  • Banding-related Adverse events

    2-4 months

Study Arms (2)

Non-latex band

EXPERIMENTAL

Non-latex bands will be placed on hemorrhoids during banding

Device: Non-Latex Band

Latex band

ACTIVE COMPARATOR

latex bands will be placed on hemorrhoids during banding

Device: Latex Band

Interventions

Hemorrhoid banding with latex band

Latex band

Hemorrhoid banding with non-latex bands

Non-latex band

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation

You may not qualify if:

  • Previous hemorrhoidal banding within the past year
  • Known latex allergy
  • Pregnancy
  • Anticoagulation use
  • Bleeding disorder
  • Portal hypertension
  • Inflammatory bowel disease
  • Immunosuppression
  • Functional neurologic disorder
  • Pelvic floor dysfunction
  • Any records flagged "break the glass" or "research opt out".

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Huntington Memorial Hospital

Pasadena, California, 91105, United States

RECRUITING

MeSH Terms

Conditions

Hemorrhoids

Condition Hierarchy (Ancestors)

Rectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Adam Truong, MD

    Huntington Health

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Investigator

Study Record Dates

First Submitted

September 11, 2024

First Posted

October 3, 2024

Study Start

August 30, 2024

Primary Completion

October 1, 2025

Study Completion (Estimated)

October 1, 2026

Last Updated

October 28, 2024

Record last verified: 2024-10

Data Sharing

IPD Sharing
Will share

Data will be available upon reasonable request

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
Time Frame
from start of study for 2 years
Access Criteria
Data will be available upon reasonable request

Locations