The Effectiveness of Interventions Targeting Self-Perception of Aging in Older Adults with Subjective Cognitive Decline

NCT06622889 | Enrolling By Invitation DMC

• 1 other identifier: PUMCSON-2023-05
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

Subjective cognitive decline (SCD) represents the initial clinical manifestation in the disease spectrum of Alzheimer's Disease (AD). It represents an essential stage for early prevention and treatment of cognitive impairment, making the SCD population an optimal target for prior intervention. This study aims to assess the feasibility and efficacy of an 8-week intervention targeting self-perception of aging in community-dwelling older adults with SCD.

Conditions

Subjective Cognitive Decline (SCD)

Keywords

Subjective Cognitive Decline; Older Adults

Outcome Measures

Primary Outcomes (1)

• Subjective Cognitive Decline

  The 9-item Subjective Cognitive Decline Questionnaire (SCD-Q9) consists of 9 items. Higher scores indicate a greater likelihood of subjective cognitive impairment.

  Baseline (pre-intervention)，8 weeks (post-intervention)，and 16 weeks (follow-up)

Secondary Outcomes (4)

• Cognitive Function

  Baseline (pre-intervention)，8 weeks (post-intervention)，and 16 weeks (follow-up)

• Self-perception of Aging

  Baseline (pre-intervention)，8 weeks (post-intervention)，and 16 weeks (follow-up)

• Perceived Stress

  Baseline (pre-intervention)，8 weeks (post-intervention)，and 16 weeks (follow-up)

• Coping Strategies

  Baseline (pre-intervention)，8 weeks (post-intervention)，and 16 weeks (follow-up)

Other Outcomes (3)

• Satisfaction questionnaire

  8 weeks (post-intervention)

• Compliance

  8 weeks (post-intervention)

• Acceptability interview

  8 weeks (post-intervention)

Study Arms (2)

8-week intervention targeting self-perception of aging

EXPERIMENTAL

Participants in this condition will receive an 8-week intervention targeting self-perception of aging. Group sessions will be held at community health service centers, with one session per week, each lasting 45 to 60 minutes. Additionally, homework assignments will be supplemented, and researchers will provide additional remote support via WeChat.

Other: Multidomain Intervention Program

Controls

NO INTERVENTION

Interventions

Multidomain Intervention Program OTHER

The intervention program aims to help older adults with subjective cognitive decline understand the aging process and adopt a positive attitude toward aging, highlighting age-related benefits. The sessions also provide emotion regulation techniques and stress-coping strategies to encourage proactive problem-solving and build confidence in handling challenges. By recalling positive life experiences, the program seeks to strengthen emotional connections, enhance the sense of belonging, and reconstruct a meaningful later life.

8-week intervention targeting self-perception of aging

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• aged ≥60 years;
• residing in the community for 6 months at least;
• experiencing a consistent decline in self-reported cognitive abilities;
• having standard cognitive test performance in the normal range;
• willing to participate in this study.

You may not qualify if:

• having diagnosis of any neurological diseases including Parkinson's disease, brain tumor, cerebral infarction, encephalitis, epilepsy, etc.;
• having diagnosis of mental illness such as depression, anxiety, bipolar disorder, and schizophrenia;
• with history of substance abuse or addiction;
• with severe visual or hearing impairment.

Sponsors & Collaborators

• Zheng Li: lead

Study Sites (1)

School of Nursing, Chinese Academy of Medical Sciences & Peking Union Medical College

Beijing, Beijing Municipality, 100144, China

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 27, 2024
• First Posted: October 2, 2024
• Study Start: November 1, 2024
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: November 29, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)