30-Second Sit-to-Stand Test for Assessing Functional Capacity in Juvenile Idiopathic Arthritis

NCT06609837 | Completed

• 1 other identifier: NArmann
• Study Type: observational
• Target: 197
• Locations: 1 country
• Sites: 1

Brief Summary

Juvenile Idiopathic Arthritis (JIA) is a heterogeneous, idiopathic, chronic inflammatory, rheumatic disease that is most common in childhood and is thought to involve immunological mechanisms in its etiopathogenesis. The physiology of children and adolescents is constantly changing due to the development and maturation of their systems. At the same time, the changes that this population shows, especially during the growth spurt and adolescence, can affect their performance in frequently used functional tests such as the 6-Minute Walk Test (6MWT). At the same time, it is emphasized that alternative tests are needed because the evaluation procedures of the 6MWT are not practical enough. The aim of this study is to investigate whether 30 Second Sit to Stand Test (30SST) is an alternative tool for assessing functional capacity in patients with JIA. H0: 30SST is not an alternative tool for assessing functional capacity in patients with JIA. H1: 30SST is an alternative tool for assessing functional capacity in patients with JIA. The study will include 81 adolescent patients with oligoarticular/polyarticular JIA and 116 healthy adolescent between the ages of 12-18. The 6MWT, 30SST and 10 Stair Climb Test (10SCT) will be applied to the cases that meet the inclusion criteria to evaluate their functional capacity. Demographic data and test results of the participants will be recorded and evaluated with statistical analysis methods. We believe that alternative tests that can be used to evaluate functional capacity in patients with JIA will contribute to the literature as a result of this study.

Conditions

Juvenile Idiopahtic Arthritis

Keywords

adolescents; Juvenile Idiopahtic Arthritis; functional capacity

Outcome Measures

Primary Outcomes (3)

• 6 Minute Walk Test (6 MWT)

  The 6MWT is a well-tolerated, easy-to-apply and simple test that shows the submaximal level of functional capacity. This test measures the distance that participants can walk quickly on a hard and flat surface in 6 minutes. Participants are rested in a chair near the starting position for at least 10 minutes before the test begins. Participants are instructed on how to perform the test. At the end of the test, the distance that participants walk in 6 minutes will be recorded in meters. The 6MWT will be used to evaluate the functional capacity of adolescents.

  Time Frame: Baseline

• 30 Second Sit to Stand Test (30SST)

  The participant will be asked to sit in a chair with the back straight; Arms will be crossed at the wrists and held towards the chest. The participant will be encouraged to complete as many sit-ups as possible in 30 seconds. The participant will be instructed to sit up completely after each sit-up. The score will be noted as the total number of sit-ups in 30 seconds.

  Time Frame: Baseline

• 10 Stairs Climb Test (10SCT)

  During the test, participants will be asked to climb 10 steps (14x28x120cm) as fast as possible. Step climbing times will be measured in seconds with a stopwatch. The 10SCT will be used to evaluate the functional capacity of adolescents.

  Time Frame: Baseline

Study Arms (2)

Usability and Validity Group

In order to evaluate the usability of the 30SST, the validity of the test will be examined. In order to determine its validity in assessing functional capacity, the correlation of 6 MWT and 10SCT will be examined.

Healthy Control Group

For analysis the difference between JIA and healthy control regarding the 30SST, 6MWT and 10SCT statistical analysis will be performed.

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Individuals with JIA who come to Istanbul University Medical Faculty, Pediatric Rheumatology Clinic and meet the inclusion criteria for Usability and Validity Group Healthy adolescent participants aged 12-18 years

You may qualify if:

• Being 12-18 years old for both groups
• Having been diagnosed with JIA at least 6 months ago at the Istanbul Medical Faculty Pediatric Rheumatology Clinic for Usability and Validity Group
• Having a diagnosis of Oligoarticular/Polyarticular JIA for Usability and Validity Group
• Volunteer to participate in the study for both groups

You may not qualify if:

• History of trauma or surgery affecting the musculoskeletal system within the last 6 months
• Having an additional chronic disease affecting the musculoskeletal system for both groups
• Having vision or hearing problems for both groups
• Having cognitive impairment at a level where the person cannot understand the commands given for both groups
• Having vision or hearing problems for both groups
• Having had a corticosteroid injection into the knee or ankle within the last week for both groups
• Difference in length in the lower extremities for both groups

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Study Sites (1)

Istanbul University-Cerrahpaşa

Istanbul, Turkey (Türkiye)

Location

Study Officials

• Nilay Arman, Assoc. Prof.

  Istanbul University - Cerrahpasa

  STUDY DIRECTOR

• Asena Yekdaneh, MSc. Pt.

  Fenerbahçe University

  PRINCIPAL INVESTIGATOR

• Asya Albayrak, MSc. Pt.

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

• Fatma Gül Demirkan, Dr.

  Istanbul University

  PRINCIPAL INVESTIGATOR

• Özlem Akgün, Assoc. Prof.

  Istanbul University

  PRINCIPAL INVESTIGATOR

• Nuray Aktay Ayaz, Prof.

  Istanbul University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 20, 2024
• First Posted: September 24, 2024
• Study Start: September 30, 2024
• Primary Completion: January 30, 2025
• Study Completion: March 30, 2025
• Last Updated: May 6, 2025

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)