Effects of Resistance-band Training and Creatine and Whey Protein

NCT06606717 | Recruiting

• 1 other identifier: 825
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.

Conditions

Sarcopenia in Elderly

Keywords

Resistance Exercise; Creatine; Whey Protein; Strength; Lean Mass

Outcome Measures

Primary Outcomes (7)

• Whole-body lean mass (kg)

  Bioelectrical impedance analysis

  baseline, week 10, week 20

• Strength (kg)

  1-repetition maximum leg press and chest press

  baseline, week 10, week 20

• Endurance (number of repetitions to fatigue)

  Leg press and chest press

  baseline, week 10, week 20

• Balance (Centre of Pressure)

  Force Plate

  baseline, week 10, week 20

• Hydration (kg)

  Bioelectrical impedance analysis

  baseline, week 10, week 20

• Gait Speed (meters)

  Walking distance

  baseline, week 10, week 20

• Muscle Hypertrophy (cm)

  B-mode ultrasound

  baseline, week 10, week 20

Study Arms (2)

Creatine Whey Protein

EXPERIMENTAL

Dietary Supplement: Creatine Whey Protein

Whey Protein

EXPERIMENTAL

Dietary Supplement: Whey Protein

Interventions

Creatine Whey Protein DIETARY_SUPPLEMENT

3 grams creatine + 30 grams whey protein

Creatine Whey Protein

Whey Protein DIETARY_SUPPLEMENT

30 grams Whey Protein

Whey Protein

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)

You may not qualify if:

• Taking creatine monohydrate within 30 days prior to the start of the study
• Currently ingesting whey protein
• Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard

Sponsors & Collaborators

• University of Regina: lead
• Iovate Health Sciences International Inc: collaborator

Study Sites (1)

University of Regina

Regina, Saskatchewan, S4S 0A2, Canada

RECRUITING

MeSH Terms

Interventions

Whey Proteins

Intervention Hierarchy (Ancestors)

Milk Proteins; Animal Proteins, Dietary; Dietary Proteins; Proteins; Amino Acids, Peptides, and Proteins; Whey; Milk; Dairy Products; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Darren Candow

  University of Regina

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Darren Candow

CONTACT

306-585-4906; Darren.Candow@uregina.ca

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 16, 2024
• First Posted: September 23, 2024
• Study Start: August 18, 2024
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: September 23, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)