Comparison of SPECT/CT Perfusion and Volumetric CT Volume

NCT06600204 | Completed

• 2 other identifiers: 2024PI070Retrospective study
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The main aim of this study is to show that single photon emission tomography/Computer tomography (SPECT/CT) is a reliable examination to predict postoperative pulmonary function after segmentectomy, by comparing this predicted function to that measured at 1 and 6 months.

Conditions

Lung Cancer (NSCLC)

Outcome Measures

Primary Outcomes (1)

• To demonstrate that SPECT/CT is a reliable examination for predicting postoperative pulmonary function after segmentectomy, by comparing this predicted function to that measured at 1 and 6 months.

  Predicted postoperative pulmonary function using SPECT/CT (% perfusion participation of the removed segment(s)). Postoperative pulmonary function measured at 1 month Postoperative pulmonary function measured at 6 months

  7 months

Study Arms (1)

Patients who underwent a single or multiple segmentectomy

Patients who underwent a single or multiple segmentectomy in the thoracic surgery department of the Nancy University Hospital between April 2021 and July 2023

Other: lung scintigraphy

Interventions

lung scintigraphy OTHER

Use the SPECT/CT to predict pulmonary function

Patients who underwent a single or multiple segmentectomy

Eligibility Criteria

• Age: 18 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Retrospective study including patients who underwent preoperative SPECT/CT pulmonary perfusion scintigraphy examination in the nuclear medicine department, from April 2021 to June 2023.

You may qualify if:

• Person having received full information on the organization of the research and not having opposed the exploitation of this data
• Patients having benefited from a single or multiple segmentectomy within the thoracic surgery department of the CHRU of Nancy during the period April 2021 to June 2023
• Patients having a complete pre-operative assessment (SPECT/CT, volumetric CT and EFR)
• Patients having 2 post-operative assessments (respiratory functional exploration (EFR) at approximately 1 month post-operatively and 6 months post-operatively).

You may not qualify if:

• Patients who underwent more extensive surgery (lobectomy, pneumectomy) or less extensive surgery (wedge).
• Patient who did not have a complete preoperative assessment (SPECT/CT or volumetric CT or missing respiratory functional exploration EFR).
• Patient who did not have a complete postoperative assessment (missing respiratory functional exploration EFR at 6 months).

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

CHRU of NANCY

Vandœuvre-lès-Nancy, 54511, France

Location

MeSH Terms

Conditions

Lung Neoplasms; Carcinoma, Non-Small-Cell Lung

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Carcinoma, Bronchogenic; Bronchial Neoplasms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 13, 2024
• First Posted: September 19, 2024
• Study Start: November 30, 2024
• Primary Completion: April 30, 2025
• Study Completion: June 1, 2025
• Last Updated: June 6, 2025

Record last verified: 2025-06

Locations

FR (1)