Exploring Long-term Risks and STI Prevalence in Pre-Exposure Prophylaxis Users in Gironde, France
SAFER-PrEP
Long-term Evolution of Risky Sexual Behaviors and Prevalence of Sexually Transmitted Infections Among Pre-Exposure Prophylaxis Users: A Retrospective Observational Study in Gironde, France
1 other identifier
observational
248
1 country
8
Brief Summary
SAFER-PrEP investigates the long-term impact of Pre-Exposure Prophylaxis (PrEP) on risky sexual behaviors and Sexually Transmitted Infection (STI) prevalence among users in Aquitaine. The study aims to compare STI rates over the last three months between individuals on PrEP for over a year and those on PrEP for less than a year. This retrospective observational research offers insights into the evolving dynamics of sexual health practices, informing future PrEP prescriptions and enhancing preventive strategies.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2024
Shorter than P25 for all trials
8 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 12, 2024
CompletedFirst Posted
Study publicly available on registry
September 19, 2024
CompletedStudy Start
First participant enrolled
November 4, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 3, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 3, 2025
CompletedSeptember 5, 2025
September 1, 2025
7 months
September 12, 2024
September 4, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Prevalence of Sexually Transmitted Infections (STIs) within the last three months
At baseline (Day 0)
Secondary Outcomes (4)
Prevalence of risky sexual behaviors in the last three months.
At baseline (Day 0)
Description of the population of PrEP users in Aquitaine.
At baseline (Day 0)
Behavioral trends in PrEP users based on self-administered questionnaires.
At baseline (Day 0)
Comparison of STI prevalence between PrEP users for over a year and those for less than a year.
At baseline (Day 0)
Study Arms (2)
PrEP less than a year
PrEP for over a year
Interventions
Standardized self-administered questionnaire specifically designed for this study.
Eligibility Criteria
Participants on Pre-Exposure Prophylaxis (PrEP) for HIV
You may qualify if:
- Aged over 18 years old;
- Participants using PrEP for at least 6 months ;
- French-speaking, without comprehension disorders ;
- being affiliated to health insurance ;
- Willing to participate and to sign informed consent.
You may not qualify if:
- Individuals with known HIV positivity;
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (8)
Cegidd de Bordeaux
Bordeaux, France
CHU de Bordeaux - Service de médecine interne et maladies infectieuses
Bordeaux, France
Maison de la Santé de l'Hôpital Saint-André - Médecine Générale
Bordeaux, France
Cabinet de Medecine Generale
Fargues-Saint-Hilaire, France
Cabinet de Medecine Generale
Le Teich, France
Cegidd de Libourne
Libourne, France
Cabinet de Medecine Generale
Mérignac, France
Cegidd de Perigueux
Périgueux, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jean-Philippe JOSEPH, Prof
jean-philippe.joseph@u-bordeaux.fr
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 12, 2024
First Posted
September 19, 2024
Study Start
November 4, 2024
Primary Completion
June 3, 2025
Study Completion
June 3, 2025
Last Updated
September 5, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share