Variables for Long-term Success in Implant Dentistry

NCT06599320 | Completed DMC

• 2 other identifiers: 2023-02279ITI n 1574_2021
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

The aims of the present retrospective 25-year study of a sample of 459 patients with 753 sandblasted and acid-etched (SLA) titanium oral implants are:

• to assess the clinical parameters at SLA implants after 25 years in function
• to assess the crestal bone levels at SLA implants after 25 years in function
• to assess and compare the microbiological conditions at SLA implants and their adjacent teeth after 25 years of function
• to assess the periodontal conditions in patients having received SLA implants 25 years ago
• to establish a baseline data set for future prospective studies on patients having received SLA implants 25 years ago
• to assess the incidence rates of biological, technical, traumatic failures / complications with SLA implants
• to assess the incidence rates of technical failures / complications with prosthetic components on SLA implants
• to assess the incidence rates of biological, technical, mechanical, esthetic failures / complications with prosthetic reconstructions on SLA implants
• to find potential risk factors for biological failures / complications with SLA implants; i.e. patients having lost their teeth due to different reasons (e.g. partial anodontia, caries, periodontitis, endodontic failure, trauma, vertical root fracture), (ii) to calculate the success rates using different thresholds set as success criteria, (iii) to evaluate the influence of medical conditions and tobacco smoking on the long-term prognosis of titanium oral implants, and (iv) to assess the frequency and quality of maintenance
• to find potential risk factors for mechanical, technical, esthetic failures/complications with reconstructions seated on SLA implants
• to assess the treatment need and utility of implant therapy after 25 years in patients having received SLA implants

Conditions

Dental Implant Failure

Keywords

dental implant; complications

Outcome Measures

Primary Outcomes (1)

• Implant survival rate

  percentage of implants in-situ

  25 years

Study Arms (1)

Partial edentulous patients rehabilitated with at least one dental implant

Partial edentulous patients rehabilitated with at least one dental implant in function for at least 20-years

Other: Oral rehabilitation with dental implants

Interventions

Oral rehabilitation with dental implants OTHER

Patients rehabilitated with implant-supported fixed partial dental prostheses

Partial edentulous patients rehabilitated with at least one dental implant

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Out of the pool of patients from the Departments of Oral Surgery and Periodontology and Fixed Prosthodontics at the University of Bern, Switzerland, all patients having received at least one dental implant will be recruited for a comprehensive evaluation 25 years after implant installation and delivery of the reconstruction. The patients had been treated according to a comprehensive treatment strategy prior to the installation of implants and incorporation of reconstructions. All patients were offered maintenance care that was provided either in the School of Dental Medicine, University of Bern, Switzerland, or in the dental practices of the referring dentists at intervals between 3 and 6 months. All the implants installed were solid screws (SS) with a diameter of 3.3, 4.1 or 4.8 mm, a length between 6-14 mm and a sandblasted and acid-etched surface (SLA) (Straumann® Dental Implant System, Institute Straumann AG, Basel, Switzerland).

You may qualify if:

• All patients rehabilitated with oral dental implants supporting fixed partial dental prostheses and followed up for at least 20-years.

You may not qualify if:

• None

Sponsors & Collaborators

• University of Bern: lead

Study Sites (1)

University of Bern

Bern, Switzerland

Location

Related Publications (1)

• Buser D, Janner SF, Wittneben JG, Bragger U, Ramseier CA, Salvi GE. 10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients. Clin Implant Dent Relat Res. 2012 Dec;14(6):839-51. doi: 10.1111/j.1708-8208.2012.00456.x.

  PMID: 22897683 RESULT

MeSH Terms

Interventions

Rehabilitation; Dental Implants

Intervention Hierarchy (Ancestors)

Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services; Dental Materials; Biomedical and Dental Materials; Dental Prosthesis; Prosthodontics; Dentistry; Prostheses and Implants; Equipment and Supplies; Manufactured Materials; Technology, Industry, and Agriculture

Study Officials

• Martin Schimmel

  University of Bern

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 25 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 5, 2024
• First Posted: September 19, 2024
• Study Start: September 9, 2024
• Primary Completion: July 30, 2025
• Study Completion: December 31, 2025
• Last Updated: January 23, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)