NCT06595862

Brief Summary

This study is an open pilot usability trial to test the 1) usability of a newly developed mobile health intervention to help manage suicidal ideation and alcohol use problems and 2) feasibility of research protocols with emerging adults (18-29 year-olds) who present to the emergency department.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
1mo left

Started Jan 2025

Geographic Reach
1 country

2 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress95%
Jan 2025May 2026

First Submitted

Initial submission to the registry

September 11, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 19, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

January 31, 2025

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2026

Last Updated

February 20, 2026

Status Verified

February 1, 2026

Enrollment Period

1.3 years

First QC Date

September 11, 2024

Last Update Submit

February 18, 2026

Conditions

Keywords

alcoholsuicidal thoughtsopen pilot trial

Outcome Measures

Primary Outcomes (3)

  • Usability of the EA-Avatar digital intervention, defined by ratings on the System Usability Scale

    If any System Usability Items are less than 3.5 out of 5, those aspects of the digital intervention will be revised in the beta version.

    12 weeks

  • Feasibility of research protocols, defined as follow-up retention

    Feasibility will be supported by retention of research participants in at least 80% at each of the four assessments

    12 weeks

  • Feasibility of research protocols, defined as adherence to the ecological momentary assessment/daily diary protocol

    Feasibility will be supported by at least 75% of total EMA and daily diary surveys across 28 days

    12 weeks

Secondary Outcomes (1)

  • Acceptability of EA-Avatar as rated on participant feedback surveys

    12 weeks

Study Arms (1)

EA-Avatar

EXPERIMENTAL

The avatar-guided digital intervention includes monitoring of alcohol use and common triggers suicidal thoughts, skills to manage alcohol use and suicidal thoughts, resources on how to access outpatient care and crisis hotlines for suicidal thoughts, and achievements for milestones. In addition, text messages provide reminders to access the avatar platform to learn or practice skills and provide encouragement. EA-Avatar is given in addition to emergency department care as usual.

Behavioral: EA-Avatar

Interventions

EA-AvatarBEHAVIORAL

The avatar-guided digital intervention includes monitoring of alcohol use and common triggers suicidal thoughts, skills to manage alcohol use and suicidal thoughts, resources on how to access outpatient care and crisis hotlines for suicidal thoughts, and achievements for milestones. In addition, text messages provide reminders to access the avatar platform to learn or practice skills and provide encouragement.

EA-Avatar

Eligibility Criteria

Age18 Years - 29 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Between 18-29 years old
  • Past month binge drinking OR score of 6 or greater on the Alcohol Use Disorder Identification Test
  • Past month active suicidal ideation per clinical chart and confirmed via self-report
  • Have a personal smartphone device with internet access
  • Speak, read, and understand English

You may not qualify if:

  • Severe cognitive delay, active psychosis, or heavy intoxication that would interfere with understanding the study
  • Imminent safety risk requiring a 1:1 observation
  • In police custody during emergency department visit
  • Unwilling or not interested in using an avatar-directed intervention in addition to their usual emergency department care

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

UMass Memorial Health - Marlborough Hospital

Marlborough, Massachusetts, 01752, United States

Location

UMass Memorial, University Campus

Worcester, Massachusetts, 05145, United States

Location

MeSH Terms

Conditions

Binge DrinkingSuicidal Ideation

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersAlcohol DrinkingDrinking BehaviorBehaviorMental DisordersSuicideSelf-Injurious BehaviorBehavioral Symptoms

Study Officials

  • Lourah M. Kelly

    UMass Worcester (UMass Chan Medical School)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: This is a single group open pilot trial, in order to test the usability of the EA-Avatar digital intervention and feasibility of the research protocols of the EA-Avatar intervention.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

September 11, 2024

First Posted

September 19, 2024

Study Start

January 31, 2025

Primary Completion (Estimated)

May 31, 2026

Study Completion (Estimated)

May 31, 2026

Last Updated

February 20, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

De-identified data will be shared with per reasonable request to the PI, after the final report and data is published in a peer-reviewed scientific journal.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
6 months after the last participant completes the study (completes their 12 week follow-up), data will be analyzed and submitted for publication in a peer-reviewed scientific journal.
Access Criteria
After publication of main and secondary outcomes in a peer-reviewed journal, de-identified data will be available upon reasonable request to the PI.

Locations