NCT06591936

Brief Summary

Genetic profile of alpha thalassemia children at sohag university hospital ,the aim to determine the prevelance , molecular character of the disorder, characterized by decreased synthesis of alpha -globin Recent work to provide mechanisms for phenotypic heterogeneity .

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 8, 2024

Completed
11 days until next milestone

First Posted

Study publicly available on registry

September 19, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2025

Completed
Last Updated

September 19, 2024

Status Verified

September 1, 2024

Enrollment Period

1 year

First QC Date

September 8, 2024

Last Update Submit

September 8, 2024

Conditions

Alpha-Thalassemia

Outcome Measures

Primary Outcomes (1)

  • PCR for prevelance of mutation phenotype

    one year

Study Arms (1)

genetic of alpha thalathemia

Eligibility Criteria

Age0 Days - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

* Acase suspecteed of alpha thalassemia * age between 0-18years * micocytic hypochromic anemia not iron deficiency anemia or Beta thalassemia

You may qualify if:

  • Acase suspecteed of alpha thalassemia
  • age between 0-18years
  • micocytic hypochromic anemia not iron deficiency anemia or Beta thalassemia

You may not qualify if:

  • Age more than 18 years
  • healthy children free from any chronic hematological disease
  • micocytic hypochromic anemia either iron deficiency anemia or Beta thalassemia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

MeSH Terms

Conditions

alpha-Thalassemia

Condition Hierarchy (Ancestors)

ThalassemiaAnemia, Hemolytic, CongenitalAnemia, HemolyticAnemiaHematologic DiseasesHemic and Lymphatic DiseasesHemoglobinopathiesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

marwa M abdelraheem, resedent doctor

CONTACT

01152389379Marwa.Abdelraheem2015@med.sohag.edu.eg

alzahraa A Ahmed, professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resedent doctor , pediatric and neonatology

Study Record Dates

First Submitted

September 8, 2024

First Posted

September 19, 2024

Study Start

August 1, 2024

Primary Completion

August 1, 2025

Study Completion

August 1, 2025

Last Updated

September 19, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will share
Shared Documents
ANALYTIC CODE
Time Frame
one year

Locations

EG(1)