ICF-Based Evaluation of the Upper Extremity in Children With Quadriparetic Cerebral Palsy

NCT06585397 | Completed

• 1 other identifier: Neslihan Yildizdagi
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Cerebral palsy (CP) is a neurodevelopmental disorder characterized by abnormalities in muscle tone, movement, and motor skills resulting from permanent, non-progressive damage to the developing brain before, during, or after birth. The worldwide prevalence of CP is 2-3 per 1000 live births. Spastic CP accounts for approximately 85% of all CP cases. Among the types of spastic CP, quadriparetic CP (QCP) is the most severe and accounts for 20% of spastic CP cases. Individuals diagnosed with quadriparetic cerebral palsy (QCP) are restricted from participating in daily life activities due to inadequate upper extremity function (spasticity, muscle weakness, inability to perform isolated movements, and limitation of supination movements). In order to correctly evaluate children diagnosed with QCP and determine treatment priorities, it is very important to evaluate them based on the International Classification of Functioning, Disability, and Health (ICF). In the literature, there is no study that evaluates the upper extremity of individuals with isolated QCP based on ICF. The aim of this study is to examine the upper extremity functions of individuals with isolated QCP diagnosis within the framework of ICF.

Conditions

Upper Extremity Spasticity; Quadriplegic Cerebral Palsy

Keywords

ICF; Body structure and function; Activity; participation; cerebral palsy; upper extremity

Outcome Measures

Primary Outcomes (3)

• Modified Ashworth Scale (MAS)

  It is a 6-point scale that measures the resistance of the muscle to passive movement by passively moving it through the normal range of motion of the joint. Within the scope of the study, the upper extremity muscles; shoulder flexors, shoulder extensors, elbow flexors, elbow extensors, forearm pronators, wrist flexors, wrist extensors, and fingers will be evaluated with MAS.

  baseline

• Manual Ability Classification System (MACS)

  It is used to classify how children with CP use their hands to handle objects in daily activities. The MACS identifies 5 levels. The MACS levels are functional descriptions based on a child's usual, self-initiated ability to handle objects in daily activities. The levels are based on children's ability to handle objects independently and their need for assistance or adaptations to perform manual activities in daily life.

  baseline

• Functional Independence Measure for Children (WeeFIM)

  It was developed to assess the functional independence levels of children with developmental disabilities in their daily living activities. The scale consists of 6 sections: self-care (6 items), sphincter control (2 items), transfers (3 items), movement (2 items), communication (2 items), and social and cognitive status (3 items). There are a total of 18 items in the sections. All items in the sections are scored from 1 to 7. 1 point indicates full dependency; 7 points indicate full independence. A total of 18 (full dependency) points and a maximum of 126 (full independence) points can be obtained.

  baseline

Study Arms (1)

Upper extremity evaluation of children with quadriparetic CP

Within the framework of ICF, the Modified Ashworth Scale, the Manual Ability Classification System and the Functional Independence Measure for Children will be applied to 20 quadriparetic children with CP.

Other: Grup 1

Interventions

Grup 1 OTHER

Within the framework of ICF, the Modified Ashworth Scale, the Manual Ability Classification System and the Functional Independence Measure for Children will be applied to 20 quadriparetic children with CP.

Upper extremity evaluation of children with quadriparetic CP

Eligibility Criteria

• Age: Up to 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Twenty quadriparetic children with CP, aged 0-17 years, will be included in the study for upper extremity evaluation.

You may qualify if:

• The age of the cases is between 0-17,
• They have been diagnosed with quadriparetic CP,
• The participants and parents want to participate in the study voluntarily.

You may not qualify if:

• Having different types of CP such as dyskinetic, ataxic and mixed type,
• Having spastic diparetic or hemiparetic type CP,
• Having any history of surgery on the musculoskeletal system,
• Having received Botulinum Toxin injection within the last 6 months.

Sponsors & Collaborators

• Acıbadem Atunizade Hospital: lead

Study Sites (1)

Acıbadem Altunizade Hospital

Istanbul, AA, 34662, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Motor Activity; Cerebral Palsy

Condition Hierarchy (Ancestors)

Behavior; Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Neslihan Yıldızdağı

  Acıbadem Atunizade Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: September 3, 2024
• First Posted: September 5, 2024
• Study Start: August 1, 2024
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)