NCT06583317

Brief Summary

This study aimed to analyses the clinical characteristics, risk factors and underlying causes as predictors of recurrent pneumonia in children attending AUCH

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
53

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2025

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 1, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 4, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

January 1, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2026

Completed
Last Updated

September 4, 2024

Status Verified

August 1, 2024

Enrollment Period

12 months

First QC Date

September 1, 2024

Last Update Submit

September 1, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • To delineate risk factors of recurrent chest infection.

    Characteristics of studied children in AUCH as in feeding, nutritional status and growth parameters.

    Baseline

Eligibility Criteria

Age30 Days - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

children with recurrent pneumonia

You may qualify if:

  • All children more than 1 month and less than 18 years of age
  • All cases presented by picture of recurrent pneumonia in the form of as at least two episodes of pneumonia in one year or three episodes ever, with radiographic clearing of densities in between.

You may not qualify if:

  • All children less than 1 month and more than 18 years
  • Evidence of malignancies
  • Evidence of congenital immune deficiency
  • Cases refusing to participate in research.
  • Cases missed for follow up.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Nair H, Simoes EA, Rudan I, Gessner BD, Azziz-Baumgartner E, Zhang JSF, Feikin DR, Mackenzie GA, Moiisi JC, Roca A, Baggett HC, Zaman SM, Singleton RJ, Lucero MG, Chandran A, Gentile A, Cohen C, Krishnan A, Bhutta ZA, Arguedas A, Clara AW, Andrade AL, Ope M, Ruvinsky RO, Hortal M, McCracken JP, Madhi SA, Bruce N, Qazi SA, Morris SS, El Arifeen S, Weber MW, Scott JAG, Brooks WA, Breiman RF, Campbell H; Severe Acute Lower Respiratory Infections Working Group. Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet. 2013 Apr 20;381(9875):1380-1390. doi: 10.1016/S0140-6736(12)61901-1. Epub 2013 Jan 29.

    PMID: 23369797BACKGROUND
  • Bhutta ZA, Das JK, Walker N, Rizvi A, Campbell H, Rudan I, Black RE; Lancet Diarrhoea and Pneumonia Interventions Study Group. Interventions to address deaths from childhood pneumonia and diarrhoea equitably: what works and at what cost? Lancet. 2013 Apr 20;381(9875):1417-1429. doi: 10.1016/S0140-6736(13)60648-0. Epub 2013 Apr 12.

    PMID: 23582723BACKGROUND

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Dalia Abdelnaser Marouf, Bachelor of Medicine

CONTACT

Maher Mokhtar Ahmed, Professor of Pediatrics

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
71515,Assiut

Study Record Dates

First Submitted

September 1, 2024

First Posted

September 4, 2024

Study Start

January 1, 2025

Primary Completion

December 31, 2025

Study Completion

January 1, 2026

Last Updated

September 4, 2024

Record last verified: 2024-08