NCT06574490

Brief Summary

The goal of this clinical trial is to learn if myofunctional therapy in 6-10-year-old children with infant type of swallowing and open bite is effective. Primary hypothesis: myofunctional therapy results in correction of open bite Researchers will compare a group in which myofunctional therapy is performed for 6 months to a group in which myoufunctional therapy will be delayed by 1 year. Participants will exercise according to a pre-established regimen and schedule

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
30mo left

Started Oct 2024

Longer than P75 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress40%
Oct 2024Oct 2028

First Submitted

Initial submission to the registry

August 13, 2024

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 28, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

October 1, 2024

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2028

Last Updated

August 28, 2024

Status Verified

August 1, 2024

Enrollment Period

3 years

First QC Date

August 13, 2024

Last Update Submit

August 25, 2024

Conditions

Keywords

open bitechildmyofunctionalmyotherapyexercises

Outcome Measures

Primary Outcomes (1)

  • Overbite

    presence positive vertical (i.e. the upper teeth overlap the lower teeth) and horizontal (i.e. the upper teeth are positioned in front of the lower teeth) occlusion

    12months

Secondary Outcomes (2)

  • Swallowing pattern

    12 months

  • Articulation

    12 months

Study Arms (2)

Myofunctional +

EXPERIMENTAL

A series of myofunctional exercises

Procedure: Myofunctional therapy (+)

Myofunctional -

ACTIVE COMPARATOR

No exercises

Procedure: Myofunctional therapy (-)

Interventions

NO exercises; A series of myofunctional exercises performed in 10-20 sessions over 6 months is delayed by 1 year

Myofunctional -

Eligibility Criteria

Age6 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • generally healthy children aged 6-10 years,
  • infant swallowing type,
  • open anterior occlusion (i.e. no contact between the maxillary and mandibular medial incisors),
  • mixed dentition

You may not qualify if:

  • finger sucking habit (or similar) occurring within the last 6 months,
  • previous myofunctional therapy,
  • upper airway obstruction,
  • congenital craniofacial developmental disorder,
  • connective tissue or muscle disease,
  • macroglossia,
  • ankyloglossia,
  • mental retardation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Open BiteMotor Activity

Interventions

Myofunctional Therapy

Condition Hierarchy (Ancestors)

MalocclusionTooth DiseasesStomatognathic DiseasesBehavior

Intervention Hierarchy (Ancestors)

Rehabilitation of Speech and Language DisordersRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesDentistry

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 13, 2024

First Posted

August 28, 2024

Study Start

October 1, 2024

Primary Completion (Estimated)

October 1, 2027

Study Completion (Estimated)

October 1, 2028

Last Updated

August 28, 2024

Record last verified: 2024-08