NCT06573333

Brief Summary

Title: Effect of timing of cord clamping of serum calcium levels in neonates Background: Hypocalcemia is a common metabolic problem in neonatal period. Most cases of hypocalcemia are asymptomatic however, the symptomatic cases require prompt management. Objective: The objective is to determine the effects of early and delayed cord on serum calcium level in neonates Study Design: Randomized Controlled Trial

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

August 24, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 27, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2024

Completed
Last Updated

August 27, 2024

Status Verified

August 1, 2024

Enrollment Period

9 months

First QC Date

August 24, 2024

Last Update Submit

August 24, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates

    Serum Calcium Levels

    at 6 hours of life

Study Arms (4)

15 seconds

EXPERIMENTAL

Umbilical Cord will be clamped after 15s of birth and Serum calcium levels will be measured at 6 hours of life

Procedure: Umblical Cord Clamping

30seconds

EXPERIMENTAL

Umbilical Cord will be clamped after 30s of birth and Serum calcium levels will be measured at 6 hours of life

Procedure: Umblical Cord Clamping

60seconds

EXPERIMENTAL

Umbilical Cord will be clamped after 60s of birth and Serum calcium levels will be measured at 6 hours of life

Procedure: Umblical Cord Clamping

120 seconds

EXPERIMENTAL

Umbilical Cord will be clamped after 120s of birth and Serum calcium levels will be measured at 6 hours of life

Procedure: Umblical Cord Clamping

Interventions

Umbilical Cord will be clamped using a plastic clamp at the noted time after delivery of the neonate

120 seconds15 seconds30seconds60seconds

Eligibility Criteria

Age1 Minute - 6 Hours
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may not qualify if:

  • Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension). Babies with congenital malformations and intrauterine growth restriction.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pak Emirates Military Hospital

Rawalpindi, Punjab Province, 45000, Pakistan

RECRUITING

Study Officials

  • Arshad Khushdil, MBBS

    Military Hospital Rawalpindi

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Umair Qureshi, MBBS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Randomised Controlled Trails
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

August 24, 2024

First Posted

August 27, 2024

Study Start

January 1, 2024

Primary Completion

September 30, 2024

Study Completion

September 30, 2024

Last Updated

August 27, 2024

Record last verified: 2024-08

Locations