NCT06565442

Brief Summary

The purpose of this study is to determine the feasibility of using the NeuraSignal transcranial doppler robot in a neuro ICU setting to measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
18mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 23, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 22, 2024

Completed
1.8 years until next milestone

Study Start

First participant enrolled

June 15, 2026

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 14, 2026

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2027

Last Updated

May 8, 2026

Status Verified

June 1, 2025

Enrollment Period

6 months

First QC Date

July 23, 2024

Last Update Submit

May 4, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary outcome

    Cerebral autoregulatory curve generation using the NeuraSignal transcranial doppler robot correlated with arterial blood pressure measurements in neuro ICU patients admitted for blood pressure management after spinal surgery

    one year

Secondary Outcomes (1)

  • Secondary outcome

    one year

Study Arms (1)

Study Group

Using the NeuraSignal transcranial doppler robot in a neuro ICU setting to measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves.

Device: NeuraSignal transcranial doppler robot

Interventions

measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves

Study Group

Eligibility Criteria

Age18 Years - 89 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients admitted to the Neuro ICU for blood pressure management (MAP management) after spinal surgery

You may qualify if:

  • Patients admitted to the Neuro ICU for blood pressure management (MAP management) after spinal surgery

You may not qualify if:

  • Patients under 18 years (or bodyweight \<50kg if age unknown),
  • prisoners
  • pregnant women,
  • non-English speaking,
  • patients enrolled in concurrent
  • ongoing interventional trial
  • students of UAB
  • employees of UAB
  • targeting specific populations
  • patients with previously diagnosed brain pathology
  • patients with open wounds over temporal bones precluding transcranial doppler

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UAB Department of Anesthesiology and Perioperative Medicine

Birmingham, Alabama, 35249, United States

Location

Study Officials

  • Emily A Wasson, MD,MPH

    University of Alabama at Birmingham

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, MPH Assistant Professor Division of Critical Care Department of Anesthesiology and Perioperative Medicine

Study Record Dates

First Submitted

July 23, 2024

First Posted

August 22, 2024

Study Start

June 15, 2026

Primary Completion (Estimated)

December 14, 2026

Study Completion (Estimated)

December 15, 2027

Last Updated

May 8, 2026

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

To be determined.

Locations