Assessment of the Association Between Visceral Obesity and the Progression of Diabetic Nephropathy

NCT06563791 | Not Yet Recruiting

• 1 other identifier: Visceral obesity and DN
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Assessment of the association between visceral obesity and the progression of diabetic nephropathy

Conditions

Diabetic Nephropathies

Outcome Measures

Primary Outcomes (1)

• Assessment of the association between visceral obesity and the progression of diabetic nephropathy

  Assessment of visceral obesity new measures as (the visceral adiposity index (VAI) , lipid accumulation product (LAP) , neck circumference (NC), waist-to-hip ratio (WHR) ) as a risk factor for the progression of diabetic nephropathy and poor renal outcome.

  Baseline

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Diabetic patients either type 1 or type 2 diabetes aged \> 18 years whether known to have diabetic nephropathy or not with BMI is ≥ 25 kg/m2

You may qualify if:

• \- 1. Diabetic patients either type 1 or type 2 diabetes aged \> 18 years whether known to have diabetic nephropathy or not.
• \. BMI is ≥ 25 kg/m2

You may not qualify if:

• \. Patients age \< 18 years. 2. BMI \< 25 kg/m2 3. Nondiabetic patients 4. Patients with non-diabetic kidney disease. 5. Patients with AKI 6. Patients with CKD stage 5 either on dialysis or not.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Thipsawat S. Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature. Diab Vasc Dis Res. 2021 Nov-Dec;18(6):14791641211058856. doi: 10.1177/14791641211058856.

  PMID: 34791910 RESULT

• Boutari C, DeMarsilis A, Mantzoros CS. Obesity and diabetes. Diabetes Res Clin Pract. 2023 Aug;202:110773. doi: 10.1016/j.diabres.2023.110773. Epub 2023 Jun 23.

  PMID: 37356727 RESULT

• Wan H, Wang Y, Xiang Q, Fang S, Chen Y, Chen C, Zhang W, Zhang H, Xia F, Wang N, Lu Y. Associations between abdominal obesity indices and diabetic complications: Chinese visceral adiposity index and neck circumference. Cardiovasc Diabetol. 2020 Jul 31;19(1):118. doi: 10.1186/s12933-020-01095-4.

  PMID: 32736628 RESULT

• Bullen AL, Katz R, Kumar U, Gutierrez OM, Sarnak MJ, Kramer HJ, Shlipak MG, Ix JH, Judd SE, Cushman M, Garimella PS. Lipid accumulation product, visceral adiposity index and risk of chronic kidney disease. BMC Nephrol. 2022 Dec 15;23(1):401. doi: 10.1186/s12882-022-03026-9.

  PMID: 36522626 RESULT

MeSH Terms

Conditions

Diabetic Nephropathies

Condition Hierarchy (Ancestors)

Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases

Central Study Contacts

Nourhan Mohamed Ehab

CONTACT

+201062839349; mohamedehabahmed204@gmail.com

Radwa awad

CONTACT

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: August 6, 2024
• First Posted: August 21, 2024
• Study Start: September 1, 2024
• Primary Completion: September 1, 2025
• Study Completion: October 1, 2025
• Last Updated: August 21, 2024

Record last verified: 2024-08