Trials Sponsors Conditions Drugs Pricing

Conditions

Epidermolysis Bullosa Dystrophica Epidermolysis Bullosa Dystrophica Dominans Epidermolysis Bullosa Dystrophica, Recessive

Keywords

Dystrophic Epidermolysis BullosaDEBCorneal Abrasions

Outcome Measures

Primary Outcomes (1)

Corneal abrasion frequency
Frequency of corneal abrasion symptoms
Baseline through up to 1 year

Secondary Outcomes (1)

Epidermolysis Bullosa Eye Disease Index Symptom Score
Baseline through up to 1 year

Eligibility Criteria

Age6 Months+

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients with Dystrophic Epidermolysis Bullosa, aged 6 months or older.

You may qualify if:

The subject or their respective legal guardian must have read, understood, and signed an Institutional Review Board (IRB) approved Informed Consent/Assent Form and must be able to and willing to follow study procedures and instructions.

Sponsors & Collaborators

Krystal Biotech, Inc.
Industrylead

Study Sites (1)

Krystal Biotech

Pittsburgh, Pennsylvania, 15203, United States

RECRUITING

Brittani AgostiniCONTACT412-586-5830 debeyestudy@krystalbio.com

MeSH Terms

Conditions

Epidermolysis Bullosa DystrophicaCorneal Injuries

Condition Hierarchy (Ancestors)

Epidermolysis BullosaSkin AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesSkin Diseases, GeneticGenetic Diseases, InbornCollagen DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesSkin DiseasesSkin Diseases, VesiculobullousEye Injuries

Central Study Contacts

David Chien, MD

CONTACT

412-586-5830 dchien@krystalbio.com

Brittani Agostini, RN, CCRC

CONTACT

412-586-5830

Study Design

Study Type: observational
Observational Model: CASE ONLY
Time Perspective: PROSPECTIVE
Sponsor Type: INDUSTRY
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 19, 2024

First Posted

August 20, 2024

Study Start

August 2, 2024

Actual (reported)

Primary Completion

December 2025

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Source record

Locations