Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.

NCT06561282 | Completed

• 1 other identifier: Konya Burn Center
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma. The main question it aims to answer is: Can the glucose-potassium ratio predict mortality in major burn patients? The glucose-to-potassium ratios of major burn patients at the time of initial hospitalization will be determined, and their relationship with mortality will be analyzed.

Conditions

Burns; Burn Injury; Inhalation Injury

Outcome Measures

Primary Outcomes (1)

• Glucose-to-potassium ratio

  The glucose-to-potassium ratio is calculated by dividing the participants' glucose values when they first apply to the hospital by their potassium values.

  2 days

Secondary Outcomes (4)

• Female/Male ratio

  2 days

• Mean percent of total body surface area burned

  2 days

• Burn infection rate

  2 days

• Mortality rate

  2 days

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of patients of all age groups who were admitted to the burn center between May 2022 and May 2024 with 2nd degree and deeper burns of 40% and above total burn surface area, 3rd and 4th degree burns of 20% and above total burn surface area, and inhalation burns. Patients with missing data, patients with burn trauma of more than 24 hours since the onset of burn trauma, 1st degree burns, patients with diabetes mellitus or renal failure, and patients using potassium-regulating drugs were excluded from the study.

You may qualify if:

• All burns \>40% of total body surface area (2nd degree or deeper)
• Burns with inhalation injury
• Burns \>20% of total body surface area 3nd degree or deeper

You may not qualify if:

• First degree burns
• Patients have more than 24 hours since the onset of burn trauma
• Patients with diabetes mellitus
• Patients with chronic renal failure
• Patients taking potassium-modifying medication
• Patients with missing data

Sponsors & Collaborators

• Konya Meram State Hospital: lead

Study Sites (1)

Konya Training and Research Hospital

Konya, 42090, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Alpaslan Sahin, Assoc. Prof.

  Principal Investigator

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: August 17, 2024
• First Posted: August 20, 2024
• Study Start: May 1, 2022
• Primary Completion: May 1, 2024
• Study Completion: July 1, 2024
• Last Updated: August 21, 2024

Record last verified: 2024-08

Locations

TU (1)