Trochlear Thickness and Its Effect on the Outcomes of Total Knee Arthroplasty

NCT06555055 | Completed

• 1 other identifier: Trochlear thickness in TKA
• Study Type: observational
• Target: 87
• Locations: 1 country
• Sites: 1

Brief Summary

Total knee arthroplasty (TKA ) is the gold standard treatment for advanced knee osteoarthritis. only 85% (75% to 92%) of patients with total knee arthroplasty are satisfied with their operations and 30% develops patellofemoral complications. Numerous biomechanical studies suggest that patellofemoral tracking is not always restored to physiological values, because the prosthetic trochlea may differ from the native trochlea. no study has been con-ducted to investigate the thickness of the trochlear groove and its effect on the outcome of Total knee replacement (TKR), So many people has different measurements of trochlear thickness which may affect Patellofemoral joint (PFJ) so knowing of native trochlear thickness in patients with KNEE Osteoarthritis (OA) can affect the outcomes of total knee arthroplasty.

Conditions

Knee Osteoarthritis

Keywords

Knee Osteoarthritis; patellofemoral; TKA; Trochlear thickness

Outcome Measures

Primary Outcomes (3)

• Functional outcome

  knee society score (KSS).

  preoperative and six months postoperatively

• Functional Outcome

  Patellofemoral score (Barlett patellofemoral score).

  preoperative and six months postoperatively

• Functional Outcome

  ROM

  preoperative and six months postoperatively

Study Arms (1)

trochlear thickness change

Radiological Assessment of trochlear thickness of PFJ in primary TKR by preoperative and postoperative CT scan. and observing Effects of Ct Different measures changes in trochlear thickness on short term TKR outcomes

Other: CT trochlear thickness change

Interventions

CT trochlear thickness change OTHER

Preoperative and postoperative CT scan measuring trochlear thickness of PFJ was defined as distance from deepest part of trochlea and line tangential to the anterior aspect of the femoral cortex. It was assessed on the sagittal cuts. CT images will be viewed using Sante DICOM viewer version 5.4.2 and image fusion will be done using Overlay multiple image software. Two observers will measure the angles and the intraobserver and interobserver reliabilities will be assessed for consistency by the intraclass correlation coefficient (ICC) and reliability coefficient using the SPSS software

trochlear thickness change

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with primary knee osteoarthritis

You may qualify if:

• Advanced knee osteoarthritis in which total knee arthroplasty is indicated

You may not qualify if:

• Revision total knee arthroplasty
• Previous osteotomy around the knee
• Post traumatic knee arthritis
• Inflammatory knee arthritis

Sponsors & Collaborators

• Ibrahim barsoum: lead
• Ain Shams University: collaborator

Study Sites (1)

Ain Sahms University

Cairo, Abbasia, 11517, Egypt

Location

Related Publications (3)

• Ranawat CS, Flynn WF Jr, Saddler S, Hansraj KK, Maynard MJ. Long-term results of the total condylar knee arthroplasty. A 15-year survivorship study. Clin Orthop Relat Res. 1993 Jan;(286):94-102.

  PMID: 8425373 RESULT

• Healy WL, Wasilewski SA, Takei R, Oberlander M. Patellofemoral complications following total knee arthroplasty. Correlation with implant design and patient risk factors. J Arthroplasty. 1995 Apr;10(2):197-201. doi: 10.1016/s0883-5403(05)80127-5.

  PMID: 7798101 RESULT

• Dejour H, Walch G, Neyret P, Adeleine P. [Dysplasia of the femoral trochlea]. Rev Chir Orthop Reparatrice Appar Mot. 1990;76(1):45-54. French.

  PMID: 2140459 RESULT

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Ibrahim B Anis, MS

  Ain Shams University

  PRINCIPAL INVESTIGATOR

• Wael S Abd El Mageed, MD

  Ain Shams University

  STUDY DIRECTOR

• Sherif M El Sayed, MD

  Ain Shams University

  STUDY DIRECTOR

• Zeiad M Zakaria, MD

  Ain Shams University

  STUDY DIRECTOR

• Mohmed E Awad, MD

  Ain Shams University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Ass. lecturer.

Study Record Dates

• First Submitted: July 14, 2024
• First Posted: August 15, 2024
• Study Start: September 30, 2022
• Primary Completion: May 1, 2024
• Study Completion: July 1, 2024
• Last Updated: August 15, 2024

Record last verified: 2024-08

Locations

EG (1)