Auto Transplantation of Wisdom Teeth
1 other identifier
interventional
20
1 country
1
Brief Summary
Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2024
CompletedFirst Submitted
Initial submission to the registry
July 29, 2024
CompletedFirst Posted
Study publicly available on registry
August 14, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2025
CompletedAugust 14, 2024
July 1, 2024
10 months
July 29, 2024
August 9, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Radiographic success
The success of auto-transplanted immature third molars with and without Platelet-Rich Fibrin will be assessed over a year period.
one year
Study Arms (2)
Autotransplantation with PRF
EXPERIMENTALAutotrasplantation only
ACTIVE COMPARATORInterventions
Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth with the application of PRF
Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth.
Eligibility Criteria
You may qualify if:
- male and female
- aged between 20 and 50 years
- devoid of systemic ailments
- complying with the study procedures
- holding an Anesthesiologists classification of 1 or 2
- possessing mandibular or maxillary immature wisdom teeth
You may not qualify if:
- systemic diseases that might impede the healing process
- Patients with pacemakers
- Individuals harboring allergies to medications or antibiotics
- active smokers
- patients afflicted with periodontal diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cleveland Dental Institute
Cleveland, Ohio, 44128, United States
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Waleed Elmallah, DDS
Cleveland Dental
- STUDY DIRECTOR
Ahmed Hashem, DDS
Cleveland Dental
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 29, 2024
First Posted
August 14, 2024
Study Start
January 1, 2024
Primary Completion
October 31, 2024
Study Completion
March 31, 2025
Last Updated
August 14, 2024
Record last verified: 2024-07