Activation of Biobank Registry for Bilio-pancreatic Diseases

NCT06552078 | Recruiting

• 1 other identifier: BIO-PANCREAS
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial bilio-pancreatic diseases, so that an evaluation of the possible association in the pathogenesis of exogenous factors with endogenous factors can be allowed. Multifactorial diseases are in fact an expression of genetic predisposition upon which one or more environmental stimuli act. Usually the aforementioned factors are not capable individually of triggering disease but, when simultaneously present, can cause the pathological phenotype. Therefore, it becomes important in the description of disease pathogenesis to identify as many risk factors for disease prevention and early diagnosis.

Conditions

Pancreatitis; Pancreatic Disease; Non-Neoplastic Pancreatic Disorder; Pancreatic Adenocarcinoma

Outcome Measures

Primary Outcomes (1)

• The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers

  The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers will be evaluated by descriptive statistics and when available compared with that of subjects without such disorders (controls).

  Tthrough study completion, an average of 1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with biliopancreatic disorders

You may qualify if:

• age \>= 18 years
• signed informed consent

You may not qualify if:

• age \< 18 years
• unwilling to sign informed consent

Sponsors & Collaborators

• IRCCS San Raffaele: lead

Study Sites (1)

IRCCS OSpedale San Raffaele

Milan, 20132, Italy

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

* peripheral blood; * portal blood; * saliva; * urine; * stool; * cystic fluid; * pancreatic juice; * biopsy tissue;

MeSH Terms

Conditions

Pancreatitis; Pancreatic Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Study Officials

• Paolo Giorgio Arcidiacono, MD

  IRCCS Ospedale San Raffaele

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gabriele Capurso, MD

CONTACT

02/26436548; capurso.gabriele@hsr.it

Laura Apadula, MSN

CONTACT

02/26433979; apadula.laura@hsr.it

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 8, 2024
• First Posted: August 13, 2024
• Study Start: June 9, 2021
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2030
• Last Updated: May 2, 2025

Record last verified: 2025-04

Locations

IT (1)