NCT06546332

Brief Summary

The general objective of this study is to evaluate the performances and the safety related to the KeriFuse® intramedullary arthrodesis implant and associated instrumentation used in accordance with their approved labelling and instruction for use. Performance and safety of KeriFuse® intramedullary arthrodesis implant will be established on short and middle-terms in regards to the implant life-cycle.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
97

participants targeted

Target at P50-P75 for all trials

Timeline
7mo left

Started Jul 2022

Longer than P75 for all trials

Geographic Reach
1 country

6 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress88%
Jul 2022Mar 2027

Study Start

First participant enrolled

July 5, 2022

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

August 6, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 9, 2024

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2027

Expected
Last Updated

September 11, 2025

Status Verified

September 1, 2025

Enrollment Period

3.4 years

First QC Date

August 6, 2024

Last Update Submit

September 4, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain and radiological assessment

    At 3 months postoperatively, the proportion of patients with a pain level ≤ 3 on VAS (ranking from 0 to 10 cm) and with a fused DIP or IP joint (radiological assessment)

    3 months

Interventions

The intramedullary arthrodesis Implant (KeriFuse®) is indicated for consolidation or bone fusion (arthrodesis) of degraded or arthritic distal interphalangeal (DIP) of hand digits or interphalangeal (IP) joint of the hand thumb.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The intended target population for the KeriFuse® and associated instruments is an adult population requiring a surgical treatment claimed by the device and presenting bone quality deemed satisfactory by the surgeon.

You may qualify if:

  • Patients ≥ 18 years,
  • Patients that will have a surgery using a KeriFuse® implant in accordance with the approved labelling and IFU.

You may not qualify if:

  • Pregnant or nursing women,
  • Patients with intellectual disabilities who cannot follow the instructions of their surgeon,
  • Patients with a contraindication to surgery and more specifically to the implantation of KeriFuse®,
  • Patients with acute or chronic infections, local or systemic,
  • Patients with sensitivities or allergies to the implant components (Nickel, Titanium).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Centre de la main du Pays d'Aix

Aix-en-Provence, 13090, France

Location

Clinique de la Chataigneraie

Beaumont, 63110, France

Location

Centre Ostéo Articulaire Fleming

Bourgoin, 38300, France

Location

Clinique Saint François

Nice, 06000, France

Location

Clinique Mutualiste Catalane

Perpignan, 66000, France

Location

Clinique du Parc

Périgueux, 24000, France

Location

MeSH Terms

Conditions

Arthritis

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 6, 2024

First Posted

August 9, 2024

Study Start

July 5, 2022

Primary Completion

December 1, 2025

Study Completion (Estimated)

March 1, 2027

Last Updated

September 11, 2025

Record last verified: 2025-09

Locations