The Role of Noncontrast Computed Tomography Markers in Predicting the Clinical Outcome of Cerebral Hemorrhage
1 other identifier
observational
1,000
0 countries
N/A
Brief Summary
The goal of this observational study is to To investigate the ability of Noncontrast Computed Tomography to predict clinical prognosis in Intracerebral Hemorrhage. The main question it aims to answer is:How to judge the prognosis of patients with cerebral hemorrhage by CT image reading at admission.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2024
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 30, 2024
CompletedStudy Start
First participant enrolled
August 1, 2024
CompletedFirst Posted
Study publicly available on registry
August 2, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2024
CompletedAugust 2, 2024
July 1, 2024
1 month
July 30, 2024
July 30, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The prognosis of cerebral hemorrhage at 90 days
The Modified Rankin Scale was used to evaluate the prognosis of the patients, and MRS Score \>2 indicated poor prognosis
90 days
Study Arms (2)
The prognosis of cerebral hemorrhage is good at 90 days
The prognosis of cerebral hemorrhage is poor at 90 days
Eligibility Criteria
Patients with cerebral hemorrhage who met the criteria and were admitted continuously within the time period
You may qualify if:
- Age≥18 years
- had completed a CT examination within 24 h of disease onset;
- had a hemorrhage that was located in the brain parenchyma, including the basal ganglia, thalamus,brain lobes, brainstem, and cerebellum.
You may not qualify if:
- had secondary ICH caused by brain trauma,cerebrovascular malformations, aneurysms, and tumors;
- had ischemic cerebral infarction hemorrhagic transformation;
- had undergone surgical treatment (e.g.hematoma removal or puncture drainage) before the CT examination;
- had images of poor quality that could notbe accurately evaluated;
- had a hematoma withborders that could not be delineated, thus precluding delineation of the region of interest (ROI).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Jin Hulead
Related Publications (1)
Wei L, Wu B, Guo T, Ru D, Gao C, Wu J, Wu A, Yue H, Hu J, Wei L, Geng Z, Wang K. Development and validation of a machine learning-based model for 90-day prognosis outcome in spontaneous intracerebral hemorrhage patients based on non-contrast computed tomography: a multicenter retrospective observational study. EClinicalMedicine. 2025 Sep 12;88:103507. doi: 10.1016/j.eclinm.2025.103507. eCollection 2025 Oct.
PMID: 41181845DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Huashan Hospital, Fudan University
Study Record Dates
First Submitted
July 30, 2024
First Posted
August 2, 2024
Study Start
August 1, 2024
Primary Completion
August 31, 2024
Study Completion
August 31, 2024
Last Updated
August 2, 2024
Record last verified: 2024-07