NCT06532708

Brief Summary

The purpose of this study is to compare opioid prescribing practices by either routine provider prescribing practices, or with the use of a calculator, i.e., the Opioid Calculator, published by the University of Michigan (www.opioidcalculator.org), with the intent of decreasing the number of pills.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 12, 2024

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

July 15, 2024

Completed
17 days until next milestone

First Posted

Study publicly available on registry

August 1, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2024

Completed
Last Updated

August 2, 2024

Status Verified

July 1, 2024

Enrollment Period

4 months

First QC Date

July 15, 2024

Last Update Submit

July 31, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of pills used

    All participants will be contacted on postoperative days 2 and 7 to inquire how many pills they have taken

    Within 1 week following surgery

Secondary Outcomes (1)

  • Postoperative pain

    Within 2 weeks following surgery

Study Arms (2)

5 Doses

EXPERIMENTAL

Participants will receive 5 doses of prescription opioids following surgery.

Other: 5x Oxycodone Oral Tablets

16 Doses

ACTIVE COMPARATOR

Participants will receive 16 doses of prescription opioids following surgery.

Other: 16x Oxycodone Oral Tablets

Interventions

Participants will be prescribed 5 doses of 5mg tablets of oxycodone for postoperative pain relief.

5 Doses

Participants will be prescribed 16 doses of 5mg tablets of oxycodone for postoperative pain relief.

16 Doses

Eligibility Criteria

Age18 Years - 80 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsWomen who are biologically female
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women aged 18 to 80
  • Undergoing planned laparoscopic hysterectomy as a day surgery procedure

You may not qualify if:

  • Women aged 18 to 80
  • Undergoing a non-laparoscopic unplanned surgical procedure
  • Patients with a history of opioid use disorder or current opioid use disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Tennessee Health Science Center

Memphis, Tennessee, 38103, United States

RECRUITING

Related Publications (2)

  • Straubhar AM, Stroup C, de Bear O, Dalton L, Rolston A, McCool K, Reynolds RK, McLean K, Siedel JH, Uppal S. Provider compliance with a tailored opioid prescribing calculator in gynecologic surgery. Gynecol Oncol. 2023 Mar;170:229-233. doi: 10.1016/j.ygyno.2023.01.018. Epub 2023 Jan 28.

    PMID: 36716511BACKGROUND
  • Wong M, Vogell A, Wright K, Isaacson K, Loring M, Morris S. Opioid use after laparoscopic hysterectomy: prescriptions, patient use, and a predictive calculator. Am J Obstet Gynecol. 2019 Mar;220(3):259.e1-259.e11. doi: 10.1016/j.ajog.2018.10.022. Epub 2018 Oct 25.

    PMID: 30837064BACKGROUND

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 15, 2024

First Posted

August 1, 2024

Study Start

July 12, 2024

Primary Completion

October 31, 2024

Study Completion

October 31, 2024

Last Updated

August 2, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations