NCT06521294

Brief Summary

This study aimed to examine the effects of the Mulligan SNAG mobilization technique, applied in addition to conventional physiotherapy on the structure of the intervertebral disc and physical functioning in patients diagnosed with low back pain due to lumbar intervertebral disc protrusion. 38 volunteer patients will participate in the study. The participants will be randomized as an interventional and control gropus.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2025

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 16, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 25, 2024

Completed
7 months until next milestone

Study Start

First participant enrolled

February 16, 2025

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2025

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2026

Completed
Last Updated

April 6, 2025

Status Verified

April 1, 2025

Enrollment Period

11 months

First QC Date

July 16, 2024

Last Update Submit

April 3, 2025

Conditions

Intervertebral Disc Protrusion

Keywords

Lumbar disc herniationMulligan Snag techniqueLow back painMRIPhysical FunctioningQuality of life

Outcome Measures

Primary Outcomes (2)

  • Magnetic Resonance Imaging

    to measure protrusion (bigger amount means worse outcome)

    baseline and iafter the intervention (in the 5th week)

  • Visual Analog Scale-VAS

    to measure pain intensity (min. score is 0 and max. score is 10- higher score means worse outcome)

    baseline and immediately after the intervention (in the 5th week)

Secondary Outcomes (7)

  • Oswestry Disability Index-ODI

    baseline and immediately after the intervention (in the 5th week)

  • Functional Independence Measure- FIM

    baseline and immediately after the intervention (in the 5th week)

  • Tampa Kinesiophobia Scale- TKS

    baseline and immediately after the intervention (in the 5th week)

  • One Leg stand Test- OLST

    before and after the intervention (in the 5th week)

  • Sit-Stand Test-SST

    before and after the intervention (in the 5th week)

  • +2 more secondary outcomes

Study Arms (2)

Group 1

EXPERIMENTAL

SNAG

Other: Mulligan SNAG mobilization tecniqueOther: Conventional Physiotherapy

Group 2

ACTIVE COMPARATOR

Physiotherapy

Other: Conventional Physiotherapy

Interventions

Mulligan SNAG mobilization tecniqueOTHER

Mulligan SNAG mobilization tecnique

Group 1
Conventional PhysiotherapyOTHER

Conventional Physiotherapy

Group 1Group 2

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Being between the ages of 20-60
  • Those diagnosed with lumbar intervertebral disc heniation (protrusion on L1-L2, L2-L3, L3-L4, L4-L5, L5-S1) at a single level
  • Those who voluntarily agreed to participate in the study

You may not qualify if:

  • Individuals diagnosed with Lumbar Bulging, Extruded, Sequestered discs
  • Individuals who have undergone lumbar region spinal surgery
  • Individuals with spinal deformity (scoliosis, spondylolisthesis, Ankylosing Spondylitis)
  • Individuals with lumbar stenosis
  • Pregnant women
  • Individuals receiving treatment for malignancy (primary or metastatic tumoral conditions in the lumbar region)
  • Individuals diagnosed with advanced osteoporosis
  • Individuals diagnosed with discitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Health Sciences in Biruni University

Istanbul, ZEYTINBURNU, 34010, Turkey (Türkiye)

Location

Related Publications (1)

  • Hussien HM, Abdel-Raoof NA, Kattabei OM, Ahmed HH. Effect of Mulligan Concept Lumbar SNAG on Chronic Nonspecific Low Back Pain. J Chiropr Med. 2017 Jun;16(2):94-102. doi: 10.1016/j.jcm.2017.01.003. Epub 2017 Mar 30.

    PMID: 28559749BACKGROUND

MeSH Terms

Conditions

Intervertebral Disc DisplacementLow Back Pain

Condition Hierarchy (Ancestors)

Spinal DiseasesBone DiseasesMusculoskeletal DiseasesHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsBack PainPainNeurologic ManifestationsSigns and Symptoms

Study Officials

  • UGUR CAVLAK, Prof.

    Biruni University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
CLINICAL PROFESSOR

Study Record Dates

First Submitted

July 16, 2024

First Posted

July 25, 2024

Study Start

February 16, 2025

Primary Completion

December 30, 2025

Study Completion

January 15, 2026

Last Updated

April 6, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)