Trials Sponsors Conditions Drugs Pricing

Conditions

Erectile Dysfunction With Diabetes Mellitus

Keywords

Erectile DysfunctionDiabetes Mellitus

Outcome Measures

Primary Outcomes (4)

Genetic alterations in the NO signaling pathway affect the degree of erectile dysfunction and the response to tadalafil treatment in patients with diabetes.
Genetic polymorphisms
3 months
Genetic variations in the folate pathway influence the degree of erectile dysfunction and the response to tadalafil treatment in patients with diabetes.
Genetic polymorphisms
3 months
Vascular wall genetic factors influence the degree of erectile dysfunction and the response to tadalafil treatment in patients with diabetes.
Genetic polymorphisms
3 months
Genetic variations in tadalafil metabolism and action pathways influence response to erectile dysfunction treatment in patients with diabetes.
Genetic polymorphisms
3 months

Study Arms (1)

Patients with diabetes and erectile dysfunction

EXPERIMENTAL

We will include in the study 90 patients with diabetes and erectile dysfunction. We will use the IIEF-5 questionnaire to confirm the diagnosis of erectile dysfunction. Patients between the ages of 40 and 65 who score 21 points or less on the IIEF-5 scale will be included in the study. Each patient will receive drug tadalafil 5 mg every day for three months.

Drug: Tadalafil 5mg

Interventions

Tadalafil 5mgDrug

Also known as: Tadilecto 5 mg

Patients with diabetes and erectile dysfunction

Eligibility Criteria

Age40 Years - 65 Years

Sexmale

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

We will include in the study 90 patients with diabetes and erectile dysfunction. We will use the IIEF-5 questionnaire to confirm the diagnosis of erectile dysfunction. Patients between the ages of 40 and 65 who score 21 points or less on the IIEF-5 scale will be included in the study.

You may not qualify if:

Sponsors & Collaborators

University Medical Centre Ljubljana
Otherlead

Study Sites (1)

University Medical Centre Ljubljana

Ljubljana, 1000, Slovenia

RECRUITING

Boštjan HostnikCONTACThostnikb@gmail.com

Boštjan HostnikPRINCIPAL INVESTIGATOR

MeSH Terms

Conditions

Erectile DysfunctionDiabetes Mellitus

Interventions

Tadalafil

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesSexual Dysfunction, PhysiologicalMale Urogenital DiseasesSexual Dysfunctions, PsychologicalMental DisordersGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

Boštjan Hostnik
University Medical Centre Ljubljana
PRINCIPAL INVESTIGATOR

Central Study Contacts

Boštjan Hostnik

CONTACT

+38641627240 hostnikb@gmail.com

Study Design

Study Type: interventional
Phase: phase 3
Allocation: NA
Masking: NONE
Purpose: BASIC SCIENCE
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: MD, internal medicine physician

Study Record Dates

First Submitted

July 22, 2024

First Posted

July 25, 2024

Study Start

May 17, 2024

Actual (reported)

Primary Completion

December 2024

Estimated (date passed)

Genetic Factors of Erectile Dysfunction Degree and Response to Tadalafil Treatment in Patients With Diabetes

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Study Arms (1)

Patients with diabetes and erectile dysfunction

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Study Arms (1)

Patients with diabetes and erectile dysfunction

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Data Sharing

Source record

Locations