NCT06518928

Brief Summary

SprmPik AI Assisted Sperm Selection Study SiD, an assistant for sperm selection during intracytoplasmic sperm injection in medically assisted reproduction: effect on fertilization, blastocyst formation, early pregnancy loss, and consistent practice. A prospective pilot study.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
155

participants targeted

Target at P50-P75 for all trials

Timeline
4mo left

Started Jan 2024

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress85%
Jan 2024Oct 2026

Study Start

First participant enrolled

January 1, 2024

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

July 19, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 25, 2024

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Expected
Last Updated

July 25, 2024

Status Verified

July 1, 2024

Enrollment Period

2 years

First QC Date

July 19, 2024

Last Update Submit

July 19, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Oocyte Fertilization

    Does SiD assist in ICSI Fertilization

    1 day

Secondary Outcomes (1)

  • Blastocyst Formation

    7 days

Study Arms (2)

AI Asssited Sperm Selection

SiD software to select sperm for ICSI

Other: Artificial Intelligence assisted sperm selection

Manual Sperm Selection

Human visualization of sperm for ICSI selection

Interventions

SiD software for sperm selection

AI Asssited Sperm Selection

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients seeking fertility treatment by ICSI.

You may qualify if:

  • Informed consent signed by the patient before treatment.
  • IVF treatments with medical or embryology indication to perform ICSI.
  • Fresh or frozen ejaculated motile sperm.
  • Selection of sperm using a 7% or 10% PVP solution.
  • Presence of motile sperm at the time of sperm selection for ICSI.
  • Partner sperm

You may not qualify if:

  • Sperm extracted by testicular biopsy.
  • That the recommendations for use of SiD have not been fully followed.
  • Inability to reliably trace sperm-oocyte-embryo throughout the process.
  • Patients with immotile sperm
  • Informed consent signed by the patient before treatment.
  • IVF treatments with medical or embryology indication to perform ICSI.
  • Cycles with at least 4 mature oocytes (Metaphase II).
  • Fresh or frozen oocytes.
  • Inability to reliably trace sperm-oocyte-embryo throughout the process.
  • Oocytes that are not in Metaphase II.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Ovation Fertility Las Vegas

Las Vegas, Nevada, 89113, United States

RECRUITING

Ovation Fertility - Austin

Austin, Texas, 78731, United States

RECRUITING

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 19, 2024

First Posted

July 25, 2024

Study Start

January 1, 2024

Primary Completion

January 1, 2026

Study Completion (Estimated)

October 1, 2026

Last Updated

July 25, 2024

Record last verified: 2024-07

Locations