NCT06515886|UnknownDMC
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Sponsor study identifier
observational
40
1 country
1
Study Start
September 22, 2022
Actual (reported)Primary Completion
December 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs. The current study will investigate if the inflammation around the implant is due to bacterial infection, hypersensitivity or both.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 22, 2022
Actual (reported)July 15, 2024
Actual (reported)July 23, 2024
Actual (reported)December 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Levels of cytokines in peri-implant crevicular fluid associated with hypersensitivity
Measure the levels of IL-4, IL-5, and IL-13 in the peri-implant crevicular fluid to assess hypersensitivity responses between healthy implants and inflamed implants (mucositis and peri-implantitis). The measured unit is pg/ml.
September 2022 - December 2024
Levels of cytokines in peri-implant crevicular fluid associated with bacterial infection
Measure the levels of IL-1α, IL-2, IL-6, IL-8, IL-10, IL-12, IL-17, TNF-α, GM-CSF, and IFN-γ in the peri-implant crevicular fluid to assess bacterial responses between healthy implants and inflamed implants (mucositis and peri-implantitis). The measured unit is pg/ml.
September 2022 - December 2024
Levels of Matrix Metalloproteinases in peri-implant crevicular fluid
Intra-oral photograph Sample of Peri-implant Crevicular fluid Clinical Examination Peri-apical x-ray
Clinical examination of a dental implant
Collection of a sample of peri-implant crevicular fluid
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
This cross-sectional study is carried out at McGill University Health Center (MUHC)-Montreal General Hospital Oral and Maxillofacial Clinic. The electronic dental records database at the MUHC Montreal General Hospital Oral and Maxillofacial Clinic is screened to identify potentially eligible participants. Individuals who had a functional implant (implant restored with a prosthesis) placed between 2010 and 2022 were reviewed. Eligible individuals are contacted and invited to participate.
Montreal General Hospital - Oral & Maxillofacial Surgery Clinic
Montreal, Quebec, H3G 1A4, Canada
Peri-implant crevicular fluid
Heba Allah Madi Dr
McGill University
Nicholas Makhoul Dr
McGill University
Jocelyne Feine Dr
McGill University
First Submitted
July 15, 2024
First Posted
July 23, 2024
Study Start
September 22, 2022
Actual (reported)Primary Completion
December 1, 2024
Estimated (date passed)Artificial Intelligence Assisted Socket Shield With Computer Guided Implant Placement
Measure the levels of MMP-1, MMP-2, and MMP-9 in the peri-implant crevicular fluid to assess hypersensitivity responses between healthy implants and inflamed implants (mucositis and peri-implantitis). The measured unit is pg/ml.
September 2022 - December 2024
Levels of RANKL in peri-implant crevicular fluid
Measure the levels of RANKL in the peri-implant crevicular fluid to assess hypersensitivity responses between healthy implants and inflamed implants (mucositis and peri-implantitis). The measured unit is pg/ml.
September 2022 - December 2024
Contact the study team to confirm eligibility.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 1, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
July 23, 2024
Record last verified: 2024-07
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Source: ClinicalTrials.gov.
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