Early Surgical Effects and Influencing Factors of High Tibial Osteotomy in the Treatment of Knee Osteoarthritis

NCT06512948 | Completed

• 1 other identifier: 0000-0001-6044-0655
• Study Type: observational
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Exploring the factors influencing postoperative functional recovery after high tibial osteotomy

Conditions

Osteoarthritis, Knee

Outcome Measures

Primary Outcomes (6)

• Imaging parameters

  Medial proximal tibial angle

  an average of 1 year after the surgery

• Imaging parameters

  Opening gap

  an average of 1 year after the surgery

• Imaging parameters

  the weight bearing line ratio

  an average of 1 year after the surgery

• Imaging parameters

  joint line convergence angle

  an average of 1 year after the surgery

• Imaging parameters

  Hip-knee-ankle

  an average of 1 year after the surgery

• Imaging parameters

  opening angle

  an average of 1 year after the surgery

Secondary Outcomes (4)

• function score

  an average of 1 year after the surgery

• function score

  an average of 1 year after the surgery

• function score

  an average of 1 year after the surgery

• function score

  an average of 1 year after the surgery

Study Arms (1)

Logistics regression model

This article is a retrospective study, which mainly incorporates patients' preoperative and postoperative imaging parameters and demographic data into Logistics regression analysis to analyze factors that may affect the surgical effect. No interventions such as medication are involved.

Procedure: High tibial osteotomy

Interventions

High tibial osteotomy PROCEDURE

Surgical treatment for patients with osteoarthritis and indications for high tibial osteotomy

Logistics regression model

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study subjects were patients who underwent medial open HTO for KOA at the First Affiliated Hospital of Shandong First Medical University from January 2018 to December 2020. This article included a total of 45 patients with grade II and grade III according to the Kellgren-Lawrence arthritis classification. There were 28 cases, including 5 grade IV patients.

You may qualify if:

• Medial knee OA, varus deformity is mainly in the tibia
• Aged ≤70 years old, with higher requirements for future activities
• Knee joint extension is limited to ≤10°, and flexion is \>90°
• Body Mass Index (BMI) ≤ 40
• No subchondral bone wear

You may not qualify if:

• There is a history of fracture or surgery of the lower limb on the operated side
• Traumatic KOA
• Combined with nerve, muscle or connective tissue diseases
• Incomplete imaging data and loss of follow-up

Sponsors & Collaborators

• Shufeng Li: lead

Study Sites (1)

The First Affiliated Hospital of Shandong First Medical University

Jinan, Shandong, 270000, China

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Zhang Zhao, professor

  Shandong First Medical University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Chief Physician

Study Record Dates

• First Submitted: January 4, 2024
• First Posted: July 22, 2024
• Study Start: January 1, 2021
• Primary Completion: December 1, 2021
• Study Completion: December 1, 2021
• Last Updated: July 22, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)