Assessment of Pancreatic Physiological and Pathological Characteristics Based on Spectral CT
1 other identifier
observational
1,500
1 country
1
Brief Summary
Patients who visited our hospital for various reasons from January 2024, underwent CT scans involving the pancreas, and were eligible for spectral post-processing reconstruction were included in the study. This research collected spectral CT data related to the pancreas at different phases, as well as physiological and pathological states for these patients. Quantitative analysis was conducted on post-processed data under different physiological and pathological states, including parameters such as pancreatic iodine uptake features, attenuation interval slopes, and extracellular volume size. In conjunction with general patient status, biochemical tests, and postoperative pathological results, the study aimed to identify correlations between parameters, develop models, and conduct research by comparing traditional CT data, which could be matched with spectral CT from the PACS database since its establishment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2021
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 21, 2021
CompletedFirst Submitted
Initial submission to the registry
June 12, 2024
CompletedFirst Posted
Study publicly available on registry
July 19, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 21, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 21, 2028
December 4, 2024
December 1, 2024
6.4 years
June 12, 2024
December 2, 2024
Conditions
Outcome Measures
Primary Outcomes (2)
spectral imaging data(SBI)
Using Philips Intellispace Portal software to reconstruct spectral imaging data images
21/3/2025
ROI area（mm2）
Using Philips Intellispace Portal software to delineate the Region of Interest (ROI)
21/3/2025
Secondary Outcomes (1)
single-energy CT value
21/3/2025
Study Arms (2)
test group
Post processing patient data using energy spectrum CT
control group
Collect traditional CT data that can correspond to spectral CT since the establishment of PACS database to form a comparison
Interventions
It will not open special sequences for patients, will not increase the cost of diagnosis and treatment, will not increase radiation exposure during enhanced CT scanning, and will not affect the normal diagnosis and treatment process of patients throughout the process.
Eligibility Criteria
Age, sex, body mass index (BMI) and grading, diabetes history, smoking history, hypertension. Patients with primary pancreatic disease who undergo surgery or biopsy according to clinical routine during their hospitalization in our hospital and obtain pathological results are included.
You may qualify if:
- Since March 2024, I have been visiting our hospital for various reasons and have undergone CT scans involving the pancreas (using energy spectrum CT)
You may not qualify if:
- Previous pancreatic surgery with incomplete pancreatic tissue.
- Severe systemic diseases that result in severe organ dysfunction
- Excessive pancreatic atrophy or other reasons cannot accurately delineate ROI
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Yu Shilead
Study Sites (1)
Shengjing Hospital of China Medical University
Shenyang, Liaoning, 110004, China
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- professor
Study Record Dates
First Submitted
June 12, 2024
First Posted
July 19, 2024
Study Start
January 21, 2021
Primary Completion (Estimated)
June 21, 2027
Study Completion (Estimated)
June 21, 2028
Last Updated
December 4, 2024
Record last verified: 2024-12