NCT06508086

Brief Summary

The aim of this study is to compare the outcomes of Karydakis technique versus sinus tract ablation procedure using 1470 nm Diode laser for the treatment of pilonidal sinus and provide evidence-based guidance to select the most appropriate operative procedure.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 10, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 12, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 18, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
Last Updated

July 18, 2024

Status Verified

July 1, 2024

Enrollment Period

12 months

First QC Date

July 12, 2024

Last Update Submit

July 12, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • recurrence rate in the treatment of pilonidal disease

    the patients undergo follow up at the outpatient clinic for manifestations of recurrence eg. discharge, multiple pits

    6 months after the operation

Study Arms (2)

group (A) LASER ABLATION

ACTIVE COMPARATOR
Procedure: laser ablation technique in the treatment of pilonidal sinus

group (B) KARYDAKIS TECHNIQUE

ACTIVE COMPARATOR
Procedure: Karydakis technique in the treatment of pilonidal sinus

Interventions

group (A) will include patients with pilonidal sinus disease who will be operated by sinus tract ablation procedure using 1470 nm Diode laser

group (A) LASER ABLATION

group (B) will include patients with pilonidal sinus disease who will be operated by Karydakis technique

group (B) KARYDAKIS TECHNIQUE

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All patients with a clinical diagnosis of symptomatic uncomplicated pilonidal sinus, males or females, any age will be included in our study.

You may not qualify if:

  • Patients with pilonidal abscess and any associated acute condition.
  • Patients with hidradenitis suppurativa.
  • Refusal.
  • Unfit for surgery.
  • Recurrence.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

  • Guner A, Cekic AB, Boz A, Turkyilmaz S, Kucuktulu U. A proposed staging system for chronic symptomatic pilonidal sinus disease and results in patients treated with stage-based approach. BMC Surg. 2016 Apr 16;16:18. doi: 10.1186/s12893-016-0134-5.

    PMID: 27084534BACKGROUND
  • Doll D, Matevossian E, Wietelmann K, Evers T, Kriner M, Petersen S. Family history of pilonidal sinus predisposes to earlier onset of disease and a 50% long-term recurrence rate. Dis Colon Rectum. 2009 Sep;52(9):1610-5. doi: 10.1007/DCR.0b013e3181a87607.

    PMID: 19690490BACKGROUND
  • Dessily M, Charara F, Ralea S, Alle JL. Pilonidal sinus destruction with a radial laser probe: technique and first Belgian experience. Acta Chir Belg. 2017 Jun;117(3):164-168. doi: 10.1080/00015458.2016.1272285. Epub 2017 Jan 6.

    PMID: 28056720BACKGROUND

MeSH Terms

Conditions

Pilonidal Sinus

Condition Hierarchy (Ancestors)

CystsNeoplasms

Central Study Contacts

Assem M Ahmed, Resident

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident, Department of General Surgery, Faculty of Medicine, Sohag University

Study Record Dates

First Submitted

July 12, 2024

First Posted

July 18, 2024

Study Start

June 10, 2024

Primary Completion

June 1, 2025

Study Completion

June 1, 2025

Last Updated

July 18, 2024

Record last verified: 2024-07

Locations