Ureteral Stent Exchange Abstention in Urinary Tract Infections

NCT06503588 | Recruiting

• 1 other identifier: 2022PI037
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The Committee of Infectiology of the French Association of Urology (CIAFU) provided, for the first time in 2020, comprehensive guidelines for ureteral stent-associated urinary tract infections (USAUTI) prevention, diagnosis and treatment. Since evidence lacked in terms of appropriate treatment, guidelines could not support systematic change of US in case of USAUTI. This study aims to evaluate whether "after guidelines group" patients treated for USAUTI had different occurrence of at least one relapse or recurrence than "before guidelines group".

Conditions

Urinary Tract Infections; Urinary Catheterization

Outcome Measures

Primary Outcomes (1)

• Relapse OR recurrence of urinary tract infection

  1 year

Secondary Outcomes (4)

• Nephro-urologic complication

  1 year

• Infectious complication

  1 year

• In-hospital and 1-year mortality

  1 year

• Resort to Watch or Reserve antibiotics

  1 year

Study Arms (2)

Before guidelines

Patients treated for ureteral stent associated urinary tract infection in the University Hospital of Nancy from January 1, 2018 to May 31, 2020

After guidelines

Patients treated for ureteral stent associated urinary tract infection in the University Hospital of Nancy from August 1, 2020 to December 31, 2022

Other: Guidelines promoting surgical abstention

Interventions

Guidelines promoting surgical abstention OTHER

Guidelines promoting surgical abstention

After guidelines

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Groups will be selected from patients attending University Hospital of Nancy meeting the eligibility criteria during the period of inclusion running from January 1, 2018 to May 31, 2020 and from August 1, 2020 to December 31, 2022

You may qualify if:

• All patients with indwelling ureteral catheter
• AND confirmed or probable urinary tract infection

You may not qualify if:

• Patient's opposition
• History of ileal conduit urinary diversion
• Second or more urinary tract infection during the study period

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Nancy university hospital

Nancy, Lorraine, 54000, France

RECRUITING

MeSH Terms

Conditions

Urinary Tract Infections

Condition Hierarchy (Ancestors)

Infections; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• +33383154097 Lefevre, M.D. PhD

  Central Hospital, Nancy, France

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Benjamin Lefevre, M.D. PhD

CONTACT

+33383154097; b.lefevre@chru-nancy.fr

Tahani Sara

CONTACT

+33383154097; s.tahani@chru-nancy.fr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD. PhD.

Study Record Dates

• First Submitted: July 10, 2024
• First Posted: July 16, 2024
• Study Start: July 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: September 1, 2025
• Last Updated: August 8, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)