NCT06499922

Brief Summary

To assess the morbidity and mortality in low grade glioma patients following surgical management.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
2mo left

Started Aug 2024

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress92%
Aug 2024Jul 2026

First Submitted

Initial submission to the registry

May 31, 2024

Completed
2 months until next milestone

First Posted

Study publicly available on registry

July 15, 2024

Completed
17 days until next milestone

Study Start

First participant enrolled

August 1, 2024

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2026

Expected
Last Updated

July 15, 2024

Status Verified

July 1, 2024

Enrollment Period

1.6 years

First QC Date

May 31, 2024

Last Update Submit

July 7, 2024

Conditions

Low Grade Glioma of Brain

Outcome Measures

Primary Outcomes (1)

  • Morbidity in low grade glioma patients following surgical management.

    report THE RATE OF POSTOPERATIVE MORBIDITY Among participants using the neurological condition assessment ( kornofisky Scale).

    2 years

Interventions

SURGICAL EXCISIONPROCEDURE

surgical excision of low grade glioma

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Each patient will be subjected to: * A complete history including personal history, history of seizures or drug intake. * General clinical examination. * Neurological examination.

You may qualify if:

  • Patients diagnosed radiologically with low grade glioma

You may not qualify if:

  • patients not fit for surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Davis ME. Epidemiology and Overview of Gliomas. Semin Oncol Nurs. 2018 Dec;34(5):420-429. doi: 10.1016/j.soncn.2018.10.001. Epub 2018 Nov 2.

    PMID: 30392758BACKGROUND

  • Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, Hawkins C, Ng HK, Pfister SM, Reifenberger G, Soffietti R, von Deimling A, Ellison DW. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-1251. doi: 10.1093/neuonc/noab106.

    PMID: 34185076BACKGROUND

  • Mazzucchi E, La Rocca G, Ius T, Sabatino G, Della Pepa GM. Multimodality Imaging Techniques to Assist Surgery in Low-Grade Gliomas. World Neurosurg. 2020 Jan;133:423-425. doi: 10.1016/j.wneu.2019.10.120. No abstract available.

    PMID: 31881559BACKGROUND

Study Officials

  • Ahmed El Gheriani, professor

    professor

    STUDY CHAIR

Central Study Contacts

Mohammad Hossam, master

CONTACT

201005663647mohammadhossam74@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

May 31, 2024

First Posted

July 15, 2024

Study Start

August 1, 2024

Primary Completion

March 1, 2026

Study Completion (Estimated)

July 1, 2026

Last Updated

July 15, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share