Lung Ultrasound Score as Post Operative Predictive Value of Pulmonary Complications in Living Liver Transplant Recipient

NCT06498895 | Not Yet Recruiting DMC FDA Device

• 1 other identifier: MD102/2024
• Study Type: observational
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to determine if lung ultrasound score has a strong predictive value for post operative pulmonary complications in living liver transplant recipient

Conditions

Pulmonary Complication; Post Operative Complication

Outcome Measures

Primary Outcomes (1)

• lung ultrasound score

  first 24 hours

Study Arms (1)

post operative living liver transplant recipient

lung ultrasound score will be done in first 24 hours in intensive care unit for living liver transplant recipient patient

Radiation: lung ultrasound

Interventions

lung ultrasound RADIATION

Lung ultrasound score will be done within one hour of admission,12 hours post admission then 24 hours in intensive care unit,follow up of patients will continue for 72 hours . a complete lung ultrasound evaluation will be performed using low frequency curved probe (2MHz-5MHz) according to the lung ultrasound score . The external lung fields will be examined by longitudinal and transverse plane scans, dividing the surface of the thorax into 12 zones: 6 on the right (anterior: upper R1 and lower R2; lateral; upper R3 and lower R4; posterior: upper R5 and lower R6) and 6 on the left side (front: upper L1 and lower L2; lateral: upper L3 and lower L4; rear: upper L5 and lower L6). LUS assigns 0 points to A lines or \< 2 separate B lines plus regular sliding; 1 point with lines B ≥ 3 or spaced focal points plus regular sliding; 2 points with coalescing B lines, and 3 points to pulmonary consolidations for each zone with a score ranging from 0 (normal lungs) to 36 (worst case scenario)

post operative living liver transplant recipient

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

• Study Population: living liver transplant recipient patients post operative in intensive care unit ( 25 patients ), all patients included in this study will be subjected to lung ultrasound score at the pre mentioned times (0,12,24) by most senior expert staff then follow up of patients in intensive care unit will reveal that patients will be divided into two groups according to occurance of lung complications to post operative pulmonary complications positive ( group that developed pulmonary complications ) and post operative pulmonary complications negative (group that didn't develop pulmonary complications ) then sensitivity, specificity and predictive value of lung ultrasound score will be determined

You may qualify if:

• living liver transplant recipient patients post operative in intensive care unit in first day
• Age ( Adults 21-60 )
• Sex ( both genders will be included )
• ASA 4 liver failure patients .

You may not qualify if:

• Presence of preoperative chronic lung diseases

Sponsors & Collaborators

• Ain Shams University: lead

Central Study Contacts

Marina refaat

CONTACT

+01202243566; marina2931994@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 6, 2024
• First Posted: July 12, 2024
• Study Start: August 25, 2025
• Primary Completion: September 10, 2025
• Study Completion: September 10, 2025
• Last Updated: August 6, 2025

Record last verified: 2024-09