The Blood Patch in the Management of Intracranial Hypotension

NCT06498804 | Recruiting

• 1 other identifier: 9059
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Intracranial hypotension results from leakage and/or hypotension of cerebrospinal fluid. It can be spontaneous or secondary to a dural puncture complicating perimedullary anesthesia or a lumbar puncture. The incidence remains low with less than 1% post spinal puncture (25 gauge needle), but is observed more frequently following a lumbar puncture, up to 36% with a 20 or 22 gauge needle. Accidental puncture of the dura mater with a 17 gauge needle used for epidural anesthesia is associated with postpuncture headaches in 75-80% of cases. Classically, symptoms appear 24 to 48 hours after the puncture and consist of very intense, postural, fronto-occipital headaches which may be associated with cranial nerve symptoms such as visual or hearing disturbances or vertigo. Among the risk factors are the size and type of the needle, age under 60 and female gender. About 90% of PDPH are self-limiting within 7-10 days.

Conditions

Intracranial Hypotension

Keywords

Intracranial Hypotension; post-dural puncture headache; cranial nerve symptoms; hearing disturbances; vertigo

Outcome Measures

Primary Outcomes (1)

• Descriptions of professional practices in the management of intracranial hypotension by blood patch at the University Hospitals of Strasbourg

  This retrospective study focuses on the description of the practices of doctors at the Strasbourg University Hospital in the management of intracranial hypotension by blood patch.

  Through study completion, an average of 2 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major subject (≥18 years old) having benefited from a bloodpatch between 01/01/2021 and 12/31/2022

You may qualify if:

• Major subject (≥18 years old)
• Subject having benefited from a bloodpatch between 01/01/2021 and 12/31/2022

You may not qualify if:

• \- Subject (and/or their legal representative if applicable) having expressed their (their) opposition to the reuse of their data for scientific research purposes

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service d'Anesthésie Réanimation médecine Péri-Opératoire - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Intracranial Hypotension; Post-Dural Puncture Headache; Vertigo

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Headache Disorders, Secondary; Headache Disorders; Vestibular Diseases; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Stefanie KOESSLER, MD

CONTACT

33 3 88 12 70 90; stefanie.koessler@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 4, 2024
• First Posted: July 12, 2024
• Study Start: September 5, 2023
• Primary Completion: December 1, 2024
• Study Completion: December 5, 2024
• Last Updated: July 12, 2024

Record last verified: 2024-04

Locations

FR (1)