NCT06497816

Brief Summary

Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life. Physical, psychological, and social impairments are seen in chronic obstructive pulmonary disease (COPD). Studies investigating the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD are limited. Therefore, the aim of this study was to compare individuals with COPD with healthy individuals in terms of health literacy, functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living and to investigate the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
144

participants targeted

Target at P50-P75 for all trials

Timeline
13mo left

Started Jun 2024

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress65%
Jun 2024Jun 2027

Study Start

First participant enrolled

June 15, 2024

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

June 28, 2024

Completed
14 days until next milestone

First Posted

Study publicly available on registry

July 12, 2024

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2027

Last Updated

July 12, 2024

Status Verified

July 1, 2024

Enrollment Period

3 years

First QC Date

June 28, 2024

Last Update Submit

July 4, 2024

Conditions

Outcome Measures

Primary Outcomes (6)

  • Functional capacity

    Functional capacity assessment using self-paced 6-minute walk test.

    1st day

  • Health literacy

    Test of Functional Health Literacy in Adults will be used to evaluate health literacy. The TOFHLA is scored on a scale of 0 to 100 and higher scores indicate higher health literacy.

    1st day

  • Health literacy

    The Rapid Estimate of Adult Literacy in Medicine questionnaires will be performed. A score of 59 or less is defined as indicating low health literacy and a score of 60 or more indicates adequate health literacy.

    1st day

  • Cognitive function

    Montreal Cognitive Assessment will be used to evaluate cognitive function. The Montreal Cognitive Assessment scores range between 0 and 30. A score of 26 or over is considered to be normal.

    1st day

  • Health-related behavior

    Health-related Behavior Scale II will be performed to assess health-related behavior. The Health-related Behavior Scale II measures various health-related behaviors and is designed to assess the frequency or extent of engagement in these behaviors. Higher scores of the scale indicate more frequent or healthier behaviors, depending on the specific behavior being measured.

    1st day

  • Functional exercise capacity

    One-minute sit to stand test will be performed. The number of repetitions will be recorded.

    1st day

Secondary Outcomes (9)

  • Forced vital capacity

    1st day

  • Forced expiratory volume in one second

    1st day

  • forced expiratory volume in one second/forced vital capacity ratio

    1st day

  • Peak expiratory flow

    1st day

  • Forced mid-expiratory flow (FEF25-75)

    1st day

  • +4 more secondary outcomes

Study Arms (2)

COPD

Individuals with stable COPD

Other: No intervention

Healthy Individuals

Healthy controls

Other: No intervention

Interventions

No intervention

COPDHealthy Individuals

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Individuals with COPD and Healthy Controls

You may qualify if:

  • Being over 40 years old,
  • Diagnosed with COPD and being clinically stable,
  • Being able to cooperate with the tests to be performed,
  • Not having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,
  • Being willing to participate in the study.

You may not qualify if:

  • Being in an acute exacerbation period,
  • Having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,
  • Not being willing to participate in the study.
  • Being willing to participate in the study and being over 40 years old
  • Not having any known disease
  • Not being able to cooperate with the tests to be performed
  • Not being willing to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University Faculty of Physical Therapy and Rehabilitation

Ankara, 06100, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic ObstructiveHealth Behavior

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBehavior

Study Officials

  • Aslihan Cakmak-Onal, PhD, PT

    Hacettepe University

    PRINCIPAL INVESTIGATOR
  • Deniz Inal-Ince, PhD, PT

    Hacettepe University

    STUDY DIRECTOR
  • Elif Kocaaga, MSc, PT

    Hacettepe University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Aslihan Cakmak-Onal, PhD, PT

CONTACT

Elif Kocaaga, MSc, PT

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 28, 2024

First Posted

July 12, 2024

Study Start

June 15, 2024

Primary Completion (Estimated)

June 15, 2027

Study Completion (Estimated)

June 15, 2027

Last Updated

July 12, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations