Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome

NCT06496022 | Active Not Recruiting

• 1 other identifier: 01-050124
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 1

Brief Summary

Assessing frailty syndrome in elderly patients in Almaty To study the features of the clinical course in the group of patients with a pre-frailty and in the group with frailty syndrome

Conditions

Frail Elderly Syndrome

Keywords

frailty; elderly; risk factors; prediction

Outcome Measures

Primary Outcomes (1)

• frailty prevalence

  A FRAIL scale or Fried frailty criteria is used (weight loss, exhaustion, low physical activity, slowness, weakness). The participants were divided into three stages: non-frail (score 0), pre-frail (score 1-2) and frail (score 3-5).

  1 March 2024 - 31 December 2024

Study Arms (1)

cohort

Patients will be divided into 2 groups: pre-frailty and frailty using Frail Scale.

Diagnostic Test: Frail scale; Diagnostic Test: Barthel scale; Diagnostic Test: SARC-F; Diagnostic Test: FRAX; Diagnostic Test: Mini-Cog scale; Diagnostic Test: dynamometry

Interventions

Frail scale DIAGNOSTIC_TEST

FRAIL scale for determining frailty (tired most of the time in the last 4 weeks; the presence of more than 5 diseases; difficulty or inability when climbing stairs and walking around the block; weight loss of more than 5% of the previous weight in the last 6 months).

cohort

Barthel scale DIAGNOSTIC_TEST

The Barthel scale is used to determine the degree of independence in daily life, the patient's household activity, the assessment of the quality of life and the necessary care.

cohort

SARC-F DIAGNOSTIC_TEST

The SARC-F scale is used to identify muscle dysfunction (difficulty lifting things over 4.5 kg, walking around the room, difficulty climbing from a chair and up 10 steps, whether the respondent has fallen in the last year).

cohort

FRAX DIAGNOSTIC_TEST

FRAX Scale (Kazakhstan platform) fracture and osteoporosis risk assessment on the website https://frax.shef.ac.uk/FRAX/tool.aspx?country=72

cohort

Mini-Cog scale DIAGNOSTIC_TEST

The Mini-Cog scale defines cognitive impairment (cognitive impairment - when scoring less than 3 points based on remembering three words and evaluating the task of drawing a clock).

cohort

dynamometry DIAGNOSTIC_TEST

carpal dynamometry (sarcopenia is exhibited at values below 26 units for men and below 16 units for women).

cohort

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients from polyclinics of nursing homes in Kazakhstan

You may qualify if:

• Patients over 60 years of age
• Signatories of the informed consent to participate in the study

You may not qualify if:

• Not agreeing to participate in scientific research
• Elderly people who do not understand the purpose of the study
• Severe and decompensated diseases that do not allow the study.
• Concomitant oncological diseases
• Concomitant neurological and mental disorders that impede the study

Sponsors & Collaborators

• Asfendiyarov Kazakh National Medical University: lead

Study Sites (1)

Kazakh National Medical University

Almaty, Tole Bi 94, 050012, Kazakhstan

Location

MeSH Terms

Conditions

Frailty

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Assistant of the department of General Medical Practice

Study Record Dates

• First Submitted: July 3, 2024
• First Posted: July 11, 2024
• Study Start: March 1, 2024
• Primary Completion: December 31, 2024
• Study Completion: March 1, 2025
• Last Updated: July 15, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

KA (1)