NCT06492668

Brief Summary

Ticks are blood-sucking arthropods that feed on vertebrate hosts. Although wild and domestic animals are the primary source of tick blood meals, humans can be an accidental host. During a blood meal, a microorganism can be transmitted to the host who can develop a disease. All infectious diseases transmitted by ticks are referred to as tick-borne diseases (TBDs). They are the most prevalent vector-borne diseases in the Northern Hemisphere. Among these diseases, Lyme borreliosis is the most common. In Europe, Lyme borreliosis does not cause high fevers (\> 38°C). Therefore, when a patient presents with a high fever with the notion of exposure to ticks, another etiology must be suspected. Anaplasma phagocytophilum and the tick-borne encephalitis virus are classically described as causing febrile syndromes. In France, ticks and tick-borne diseases are increasing, particularly those associated with the Ixodes ricinus tick. This tick is mainly present in forest ecosystems with a peak of activity in May. Foresters represent a population with biting ticks and tick-borne diseases, notably Lyme borreliosis.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 1, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 9, 2024

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2025

Completed
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 8, 2025

Completed
Last Updated

July 15, 2024

Status Verified

July 1, 2024

Enrollment Period

1.5 years

First QC Date

July 1, 2024

Last Update Submit

July 11, 2024

Conditions

Keywords

Tick-Borne DiseasesLyme borreliosisFebrile syndromesIxodes ricinus tick

Outcome Measures

Primary Outcomes (1)

  • Number of ticks found on clothing during activities in forest ecosystems, and if tick bites, their number.

    This study is carried out on foresters in the Alsacce region over a period of one year.

    1 year

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Major forester (≥18 years old), ONF (National Forestry Office) staff regularly exposed to ticks in Alsace.

You may qualify if:

  • Major forester (≥18 years old)
  • Male or female gender
  • ONF (National Forestry Office) staff
  • Regularly exposed to ticks in Alsace (exclusively)
  • Practicing regular forestry activities in a group
  • Agreeing to participate in the study.

You may not qualify if:

  • Refusal to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre National de Référence Borrelia - CHU de Strasbourg - France

Strasbourg, Les Hôpitaux Universitaires de Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Lyme DiseaseTick-Borne Diseases

Condition Hierarchy (Ancestors)

Gram-Negative Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsBorrelia InfectionsSpirochaetales InfectionsVector Borne Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 1, 2024

First Posted

July 9, 2024

Study Start

January 1, 2024

Primary Completion

July 1, 2025

Study Completion

July 8, 2025

Last Updated

July 15, 2024

Record last verified: 2024-07

Locations